MedKoo Cat#: 562352 | Name: BisQ

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BisQ is a photochromic agonist for the muscle-type nAChR.

Chemical Structure

BisQ
BisQ
CAS#73711-18-9

Theoretical Analysis

MedKoo Cat#: 562352

Name: BisQ

CAS#: 73711-18-9

Chemical Formula: C20H30I2N4

Exact Mass: 580.0560

Molecular Weight: 580.29

Elemental Analysis: C, 41.40; H, 5.21; I, 43.74; N, 9.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
BisQ; Bis-Q; Bis Q;
IUPAC/Chemical Name
(E)-1,1'-Diazene-1,2-diylbis(4,1-phenylene)bis(N,N,N-trimethylmethananaminium) iodide
InChi Key
MECSIHVOSZRVFP-ZPZFBZIMSA-L
InChi Code
InChI=1S/C20H30N4.2HI/c1-23(2,3)15-17-7-11-19(12-8-17)21-22-20-13-9-18(10-14-20)16-24(4,5)6;;/h7-14H,15-16H2,1-6H3;2*1H/q+2;;/p-2/b22-21+;;
SMILES Code
C[N+](C)(C)CC1=CC=C(/N=N/C2=CC=C(C[N+](C)(C)C)C=C2)C=C1.[I-].[I-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 580.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sensaki S, Sabanayagam C, Chua S, Htoon HM, Broekman BFP, Thiam DGY, Ngo C, Saw SM. Sleep Duration in Infants Was Not Associated With Myopia at 3 Years. Asia Pac J Ophthalmol (Phila). 2018 Mar-Apr;7(2):102-108. doi: 10.22608/APO.2017390. Epub 2018 Feb 26. PubMed PMID: 29480655. 2: Mindell JA, Lee CI, Leichman ES, Rotella KN. Massage-based bedtime routine: impact on sleep and mood in infants and mothers. Sleep Med. 2018 Jan;41:51-57. doi: 10.1016/j.sleep.2017.09.010. Epub 2017 Oct 10. PubMed PMID: 29425578. 3: Cavalheiro MG, Corrêa CC, Maximino LP, Weber SAT. Sleep quality in children: questionnaires available in Brazil. Sleep Sci. 2017 Oct-Dec;10(4):154-160. doi: 10.5935/1984-0063.20170027. PubMed PMID: 29410747; PubMed Central PMCID: PMC5760049. 4: Cassanello P, Díez-Izquierdo A, Gorina N, Matilla-Santander N, Martínez-Sanchez JM, Balaguer A. [Adaptation and study of the measurement properties of a sleep questionnaire for infants and pre-school children]. An Pediatr (Barc). 2018 Jan 6. pii: S1695-4033(17)30468-X. doi: 10.1016/j.anpedi.2017.12.003. [Epub ahead of print] Spanish. PubMed PMID: 29317179. 5: Zhou K, He X, Huo L, An J, Li M, Wang W, Li X. Development of the body image self-rating questionnaire for breast cancer (BISQ-BC) for Chinese mainland patients. BMC Cancer. 2018 Jan 4;18(1):19. doi: 10.1186/s12885-017-3865-5. PubMed PMID: 29301503; PubMed Central PMCID: PMC5753569. 6: Chen YX, Erigene XY, Wu K, Huang WP, Yu SH, Chen HY, Ye AH, Zhang FB, Tao F. [Emotional and behavioral problems associated with sleep problems in preschool aged children]. Zhonghua Liu Xing Bing Xue Za Zhi. 2017 Sep 10;38(9):1191-1196. doi: 10.3760/cma.j.issn.0254-6450.2017.09.010. Chinese. PubMed PMID: 28910930. 7: Wang X, Gao X, Yang Q, Wang X, Li S, Jiang F, Zhang J, Ouyang F. Sleep disorders and allergic diseases in Chinese toddlers. Sleep Med. 2017 Sep;37:174-179. doi: 10.1016/j.sleep.2017.02.011. Epub 2017 Mar 7. PubMed PMID: 28899531. 8: Caravale B, Sette S, Cannoni E, Marano A, Riolo E, Devescovi A, De Curtis M, Bruni O. Sleep Characteristics and Temperament in Preterm Children at Two Years of Age. J Clin Sleep Med. 2017 Sep 15;13(9):1081-1088. doi: 10.5664/jcsm.6728. PubMed PMID: 28760193; PubMed Central PMCID: PMC5566464. 9: Yang F, Lin QM, Wang GH, Jiang YR, Song YJ, Dong SM, Sun WQ, Deng YJ, Wang Y, Xu XJ, Zhu Q, Jiang F. [Investigation of dose-dependent association between bedtime routines and sleep outcomes in infants and toddlers]. Zhonghua Er Ke Za Zhi. 2017 Jun 2;55(6):439-444. doi: 10.3760/cma.j.issn.0578-1310.2017.06.009. Chinese. PubMed PMID: 28592012. 10: Dogan DG, Canaloglu SK, Kivilcim M, Kum YE, Topal E, Catal F. Sleep patterns of young children with newly diagnosed atopic dermatitis. Postepy Dermatol Alergol. 2017 Apr;34(2):143-147. doi: 10.5114/ada.2017.67080. Epub 2017 Apr 13. PubMed PMID: 28507494; PubMed Central PMCID: PMC5420607. 11: Hager ER, Calamaro CJ, Bentley LM, Hurley KM, Wang Y, Black MM. Nighttime Sleep Duration and Sleep Behaviors among Toddlers from Low-Income Families: Associations with Obesogenic Behaviors and Obesity and the Role of Parenting. Child Obes. 2016 Oct;12(5):392-400. doi: 10.1089/chi.2015.0252. Epub 2016 Jul 22. PubMed PMID: 27447782; PubMed Central PMCID: PMC5041548. 12: Thomas KA, Spieker S. Sleep, Depression, and Fatigue in Late Postpartum. MCN Am J Matern Child Nurs. 2016 Mar-Apr;41(2):104-9. doi: 10.1097/NMC.0000000000000213. PubMed PMID: 26909724; PubMed Central PMCID: PMC4770802. 13: Dong S, Song Y, Jiang Y, Sun W, Wang Y, Jiang F. [Multi-center study on the effects of television viewing on sleep quality among children under 4 years of age in China]. Zhonghua Er Ke Za Zhi. 2015 Dec;53(12):907-12. Chinese. PubMed PMID: 26887545. 14: Hysing M, Sivertsen B, Garthus-Niegel S, Eberhard-Gran M. Pediatric sleep problems and social-emotional problems. A population-based study. Infant Behav Dev. 2016 Feb;42:111-8. doi: 10.1016/j.infbeh.2015.12.005. Epub 2016 Jan 8. PubMed PMID: 26774862. 15: Butler R, Moore M, Mindell JA. Pacifier Use, Finger Sucking, and Infant Sleep. Behav Sleep Med. 2016 Nov-Dec;14(6):615-23. doi: 10.1080/15402002.2015.1048451. Epub 2015 Nov 7. PubMed PMID: 26548755. 16: Damijonaitis A, Broichhagen J, Urushima T, Hüll K, Nagpal J, Laprell L, Schönberger M, Woodmansee DH, Rafiq A, Sumser MP, Kummer W, Gottschalk A, Trauner D. AzoCholine Enables Optical Control of Alpha 7 Nicotinic Acetylcholine Receptors in Neural Networks. ACS Chem Neurosci. 2015 May 20;6(5):701-7. doi: 10.1021/acschemneuro.5b00030. Epub 2015 Mar 27. PubMed PMID: 25741856. 17: Huang YS, Paiva T, Hsu JF, Kuo MC, Guilleminault C. Sleep and breathing in premature infants at 6 months post-natal age. BMC Pediatr. 2014 Dec 16;14:303. doi: 10.1186/s12887-014-0303-6. PubMed PMID: 25510740; PubMed Central PMCID: PMC4272529. 18: Carpa R, Keul A, Muntean V, Dobrotă C. Characterization of halophilic bacterial communities in Turda Salt Mine (Romania). Orig Life Evol Biosph. 2014 Sep;44(3):223-30. doi: 10.1007/s11084-014-9375-4. Epub 2014 Dec 5. PubMed PMID: 25476992; PubMed Central PMCID: PMC4669543. 19: Fu R, O'Reilly ME, Nielsen RJ, Goddard WA 3rd, Gunnoe TB. Rhodium bis(quinolinyl)benzene complexes for methane activation and functionalization. Chemistry. 2015 Jan 12;21(3):1286-93. doi: 10.1002/chem.201405460. Epub 2014 Nov 21. PubMed PMID: 25418788. 20: Fernández Miaja M, Rodríguez Fernández C, Fernández Pérez ML, Mata Zubillaga D, Miaja Quiñones J, Rodríguez Fernández LM. [Amount of sleep and changes in its patterns in children less than two years old]. An Pediatr (Barc). 2015 Feb;82(2):89-94. doi: 10.1016/j.anpedi.2014.02.002. Epub 2014 Apr 13. Spanish. PubMed PMID: 24735909.