MedKoo Cat#: 527788 | Name: GNF7686

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GNF7686 is a novel inhibitor of Trypanosoma cruzi, the causative agent of Chagas disease.

Chemical Structure

GNF7686
GNF7686
CAS#442567-43-3

Theoretical Analysis

MedKoo Cat#: 527788

Name: GNF7686

CAS#: 442567-43-3

Chemical Formula: C15H13N3O

Exact Mass: 251.1059

Molecular Weight: 251.29

Elemental Analysis: C, 71.70; H, 5.21; N, 16.72; O, 6.37

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
GNF7686; GNF-7686; GNF 7686
IUPAC/Chemical Name
2-Ethyl-1-hydroxy-3-methyl-pyrido[1,2-a]benzimidazole-4-carbonitrile
InChi Key
ICOJYIYMSJTRKZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H13N3O/c1-3-10-9(2)11(8-16)14-17-12-6-4-5-7-13(12)18(14)15(10)19/h4-7,19H,3H2,1-2H3
SMILES Code
N#CC1=C(C)C(CC)=C(O)N2C3=CC=CC=C3N=C21
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 251.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Khare S, Roach SL, Barnes SW, Hoepfner D, Walker JR, Chatterjee AK, Neitz RJ, Arkin MR, McNamara CW, Ballard J, Lai Y, Fu Y, Molteni V, Yeh V, McKerrow JH, Glynne RJ, Supek F. Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease. PLoS Pathog. 2015 Jul 17;11(7):e1005058. doi: 10.1371/journal.ppat.1005058. eCollection 2015 Jul. PubMed PMID: 26186534; PubMed Central PMCID: PMC4506092.