JH-XI-10-02 is a potent and selective CDK8 inhibitor. JH-XI-10-02 can recruit the E3 ligase CRL4Cereblon to promote the ubiquitination and proteosomal degradation of CDK8.
MedKoo Cat#: 407891
Name: JH-XI-10-02
CAS#: 2209085-22-1
Chemical Formula: C53H69N5O9
Exact Mass: 919.5095
Molecular Weight: 920.16
Elemental Analysis: C, 69.18; H, 7.56; N, 7.61; O, 15.65
The following data is based on the product molecular weight 920.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
