MedKoo Cat#: 562303 | Name: MP-A08
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MP-A08 is a Selective ATP-competitive sphingosine kinase inhibitor. It also demonstrates anti-cancer properties.

Chemical Structure

MP-A08
MP-A08
CAS#219832-49-2

Theoretical Analysis

MedKoo Cat#: 562303

Name: MP-A08

CAS#: 219832-49-2

Chemical Formula: C27H25N3O4S2

Exact Mass: 519.1286

Molecular Weight: 519.63

Elemental Analysis: C, 62.41; H, 4.85; N, 8.09; O, 12.32; S, 12.34

Price and Availability

Size Price Availability Quantity
5mg USD 285.00 2 Weeks
10mg USD 450.00 2 Weeks
25mg USD 850.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
MP-A08; MP A08; MPA08; NSC-122314; NSC 122314; NSC122314;
IUPAC/Chemical Name
4-Methyl-N-[2-[[[2-[[(4-methylphenyl)sulfonyl]amino]phenyl]imino]methyl]phenyl]-benzenesulfonamide
InChi Key
FLDBNMYJUMAXDQ-TURZUDJPSA-N
InChi Code
InChI=1S/C27H25N3O4S2/c1-20-11-15-23(16-12-20)35(31,32)29-25-8-4-3-7-22(25)19-28-26-9-5-6-10-27(26)30-36(33,34)24-17-13-21(2)14-18-24/h3-19,29-30H,1-2H3/b28-19+
SMILES Code
O=S(C1=CC=C(C)C=C1)(NC2=CC=CC=C2/C=N/C3=CC=CC=C3NS(=O)(C4=CC=C(C)C=C4)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 519.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Dimasi DP, Pitson SM, Bonder CS. Examining the Role of Sphingosine Kinase-2 in the Regulation of Endothelial Cell Barrier Integrity. Microcirculation. 2016 Apr;23(3):248-65. doi: 10.1111/micc.12271. PubMed PMID: 26822263. 2: Pitman MR, Powell JA, Coolen C, Moretti PA, Zebol JR, Pham DH, Finnie JW, Don AS, Ebert LM, Bonder CS, Gliddon BL, Pitson SM. A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties. Oncotarget. 2015 Mar 30;6(9):7065-83. PubMed PMID: 25788259; PubMed Central PMCID: PMC4466670.