Synonym
YM 9429; YM-9429; YM9429.
IUPAC/Chemical Name
Piperidine, 1-(4-(1-methyl-1-(4-methylcyclohexyl)ethoxy)phenyl)-, cis-
InChi Key
HVXJILXIZHJUAE-HDICACEKSA-N
InChi Code
InChI=1S/C21H33NO/c1-17-7-9-18(10-8-17)21(2,3)23-20-13-11-19(12-14-20)22-15-5-4-6-16-22/h11-14,17-18H,4-10,15-16H2,1-3H3/t17-,18+
SMILES Code
C1CCCN(C1)c1ccc(OC([C@H]2CC[C@H](CC2)C)(C)C)cc1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
315.50
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Numazawa S, Shibata M, Imaoka S, Funae Y, Yoshida T. Induction of hepatic CYP2B1/2 by a teratogenic compound cis-1-[-4-(p-menthane-8-yloxy)phenyl]piperadine (YM9429) in rats. J Toxicol Sci. 2000 Feb;25(1):57-61. PubMed PMID: 10736791.
2: Honda A, Tint GS, Shefer S, Batta AK, Honda M, Salen G. Effect of YM 9429, a potent teratogen, on cholesterol biosynthesis in cultured cells and rat liver microsomes. Steroids. 1996 Sep;61(9):544-8. PubMed PMID: 8883221.
3: Shibata M, Fujino E, Sato Y, Numazawa S, Yoshida T, Kuroiwa Y. Inhibition of insulin-induced chondrogenic differentiation of embryonic carcinoma cells by a teratogenic compound YM9429. Biochem Biophys Res Commun. 1996 Aug 14;225(2):593-9. PubMed PMID: 8753805.
4: Shibata M, Watanabe T. In vitro assessment of teratogenic potential of cis-1-[4-(p-menthane-8-yloxy) phenyl]piperidine [corrected]. J Toxicol Sci. 1995 Feb;20(1):9-14. Erratum in: J Toxicol Sci 1996 Aug;21(3):205. PubMed PMID: 7595978.
5: Shibata M. A new potent teratogen in CD rats inducing cleft palate. J Toxicol Sci. 1993 Aug;18(3):171-8. Erratum in: J Toxicol Sci 1994 Nov;19(4):239. PubMed PMID: 8246309.
