MedKoo Cat#: 527780 | Name: GV2-20

Description:

WARNING: This product is for research use only, not for human or veterinary use.

GV2-20 is a potent inhibitor of cabonic anhydrase 2 (CA2).

Chemical Structure

GV2-20
GV2-20
CAS#346411-65-2

Theoretical Analysis

MedKoo Cat#: 527780

Name: GV2-20

CAS#: 346411-65-2

Chemical Formula: C15H13N3O6

Exact Mass: 331.0804

Molecular Weight: 331.28

Elemental Analysis: C, 54.38; H, 3.96; N, 12.68; O, 28.98

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
GV220; GV2 20; GV2-20
IUPAC/Chemical Name
3,5-Dinitro-4-[(2-phenylethyl)amino]benzoic acid
InChi Key
XAKDDYXCEWRWEZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H13N3O6/c19-15(20)11-8-12(17(21)22)14(13(9-11)18(23)24)16-7-6-10-4-2-1-3-5-10/h1-5,8-9,16H,6-7H2,(H,19,20)
SMILES Code
O=C(O)C1=CC([N+]([O-])=O)=C(NCCC2=CC=CC=C2)C([N+]([O-])=O)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 331.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Mori M, Cau Y, Vignaroli G, Laurenzana I, Caivano A, Vullo D, Supuran CT, Botta M. Hit Recycling: Discovery of a Potent Carbonic Anhydrase Inhibitor by in Silico Target Fishing. ACS Chem Biol. 2015 Sep 18;10(9):1964-9. doi: 10.1021/acschembio.5b00337. Epub 2015 Jul 1. PubMed PMID: 26121309. 2: He GH, Ruan JW, Zeng YS, Zhou X, Ding Y, Zhou GH. Improvement in acupoint selection for acupuncture of nerves surrounding the injury site: electro-acupuncture with Governor vessel with local meridian acupoints. Neural Regen Res. 2015 Jan;10(1):128-35. doi: 10.4103/1673-5374.150720. PubMed PMID: 25788933; PubMed Central PMCID: PMC4357096. 3: Kim HY, Wang J, Lee I, Kim HK, Chung K, Chung JM. Electroacupuncture suppresses capsaicin-induced secondary hyperalgesia through an endogenous spinal opioid mechanism. Pain. 2009 Oct;145(3):332-40. doi: 10.1016/j.pain.2009.06.035. Epub 2009 Jul 30. PubMed PMID: 19646817; PubMed Central PMCID: PMC2762198. 4: Chen YY, Zhang W, Chen YL, Chen SJ, Dong H, Zeng YS. Electro-acupuncture improves survival and migration of transplanted neural stem cells in injured spinal cord in rats. Acupunct Electrother Res. 2008;33(1-2):19-31. PubMed PMID: 18672742. 5: Sui HS, Liu Y, Miao DQ, Yuan JH, Qiao TW, Luo MJ, Tan JH. Configurations of germinal vesicle (GV) chromatin in the goat differ from those of other species. Mol Reprod Dev. 2005 Jun;71(2):227-36. PubMed PMID: 15791590. 6: Hughes GJ, Páez A, Bóshell J, Rupprecht CE. A phylogenetic reconstruction of the epidemiological history of canine rabies virus variants in Colombia. Infect Genet Evol. 2004 Mar;4(1):45-51. PubMed PMID: 15019589. 7: Beard SJ, Handley BA, Hayes PK, Walsby AE. The diversity of gas vesicle genes in Planktothrix rubescens from Lake Zürich. Microbiology. 1999 Oct;145 ( Pt 10):2757-68. PubMed PMID: 10537197.