Nafiverine is a new antispasmodic. The stability of nafiverine, in an aqueous solution and in rabbit plasma was investigated. Metabolites of nafiverine in blood, bile, and urine were determined quantitatively. The effectiveness of an intramuscular administration of nafiverine was comparable to that of an intravenous administration. One metabolite of nafiverine, N-(2-hydroxyethyl)-N'-[alpha-(naphthyl)propionyloxy-2-ethyl]piperazine, is a new compound.
MedKoo Cat#: 581125
Name: Nafiverine
CAS#: 5061-22-3
Chemical Formula: C30H22N4O4
Exact Mass: 502.1641
Molecular Weight: 502.53
Elemental Analysis: C, 71.70; H, 4.41; N, 11.15; O, 12.73
The following data is based on the product molecular weight 502.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
