Cajucarinolide | CAS#147742-03-8 | anti-inflammatory

MedKoo Cat#: 584366 | Name: Cajucarinolide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cajucarinolide is a clerodane diterpene isolated from the cortices of Croton cajucara (Euphorbiaceae). This compound possesses anti-inflammatory activity and inhibits bee venom phospholipase A2 in vitro.

Chemical Structure

Cajucarinolide

CAS#147742-03-8

Theoretical Analysis

MedKoo Cat#: 584366

Name: Cajucarinolide

CAS#: 147742-03-8

Chemical Formula: C19H22O6

Exact Mass: 346.1416

Molecular Weight: 346.38

Elemental Analysis: C, 65.88; H, 6.40; O, 27.71

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Cajucarinolide

IUPAC/Chemical Name

Spiro(furan-3(2H),1'(7'H)-naphthalene)-2,7'-dione, 5-(2,5-dihydro-5-hydroxy-2-oxo-3-furanyl)-2',3',4,4',4'a,5,8',8'a-octahydro-2',5'-dimethyl-

InChi Key

KDHLKFOOPWLPCD-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H22O6/c1-9-5-11(20)6-14-12(9)4-3-10(2)19(14)8-15(24-18(19)23)13-7-16(21)25-17(13)22/h5,7,10,12,14-16,21H,3-4,6,8H2,1-2H3

SMILES Code

O=C1OC(C2=CC(O)OC2=O)CC13C(C)CCC4C(C)=CC(CC43)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 346.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ichihara Y, Takeya K, Hitotsuyanagi Y, Morita H, Okuyama S, Suganuma M, Fujiki H, Motidome M, Itokawa H. Cajucarinolide and isocajucarinolide: anti-inflammatory diterpenes from Croton cajucara. Planta Med. 1992 Dec;58(6):549-51. PubMed PMID: 1484896. 2: Maciel MA, Pinto AC, Arruda AC, Pamplona SG, Vanderlinde FA, Lapa AJ, Echevarria A, Grynberg NF, Côlus IM, Farias RA, Luna Costa AM, Rao VS. Ethnopharmacology, phytochemistry and pharmacology: a successful combination in the study of Croton cajucara. J Ethnopharmacol. 2000 Apr;70(1):41-55. PubMed PMID: 10720788.