MedKoo Cat#: 581118 | Name: Nematocyphol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nematocyphol is triterpene constituents from Euphorbia nematocypha Hand-Mazz. Seven triterpenoids have been isolated from the roots of Euphorbia nematocypha Hand-Mazz. through chromatography on 20% AgNO3-silica gel. One of them was identified as a new compound named nematocyphol on the basis of spectral data (IR, EIMS, 1H-NMR and 13C-NMR). Its structure was deduced as IVa. Other compounds were identified as nepehinol acetate (I), germanicol acetate (II), euphol (III), tanaxastanol (Va), 24-methylenecycloartanol (VIa) and nepehinol (VIIa). These compounds were obtained for the first time from this plant.

Chemical Structure

Nematocyphol
Nematocyphol
CAS#143490-50-0

Theoretical Analysis

MedKoo Cat#: 581118

Name: Nematocyphol

CAS#: 143490-50-0

Chemical Formula: C30H50O

Exact Mass: 426.3862

Molecular Weight: 426.73

Elemental Analysis: C, 84.44; H, 11.81; O, 3.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Nematocyphol;
IUPAC/Chemical Name
(1R,3aR,5aS,7aR,9S,11aR,11bR,13aS,13bR)-1-isopropyl-3a,5a,8,8,11a,13a-hexamethyl-2,3,3a,4,5,5a,7,7a,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-ol
InChi Key
QOYZWNYLMKAORW-AFYZKSQYSA-N
InChi Code
InChI=1S/C30H50O/c1-19(2)20-11-14-27(5)17-18-29(7)22-9-10-23-26(3,4)24(31)13-15-28(23,6)21(22)12-16-30(29,8)25(20)27/h9,19-21,23-25,31H,10-18H2,1-8H3/t20-,21+,23+,24+,25-,27-,28-,29-,30+/m1/s1
SMILES Code
CC(C)[C@H]1CC[C@]2([C@H]1[C@@]3(CC[C@H]4C(=CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)[C@]3(CC2)C)C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 426.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Cao D, Su YL, Yang JS. [Triterpene constituents from Euphorbia nematocypha Hand-Mazz]. Yao Xue Xue Bao. 1992;27(6):445-51. Chinese. PubMed PMID: 1442072.