MedKoo Cat#: 555176 | Name: UBP714
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

UBP714 is a derivative of the NMDA receptor negative allosteric modulator UBP608 (SML0606). UBP714 also enhanced NMDAR mediated field EPSPs in the CA1 region of the hippocampus. UBP714 is therefore a novel template for the development of potent and subunit selective NMDAR potentiators that may have therapeutic applicability in the treatment of patients with cognitive deficits or schizophrenia.

Chemical Structure

UBP714
UBP714
CAS#773109-55-0

Theoretical Analysis

MedKoo Cat#: 555176

Name: UBP714

CAS#: 773109-55-0

Chemical Formula: C11H7BrO4

Exact Mass: 281.9528

Molecular Weight: 283.08

Elemental Analysis: C, 46.67; H, 2.49; Br, 28.23; O, 22.61

Price and Availability

Size Price Availability Quantity
1g USD 3,850.00 2-3 months
2g USD 6,850.00 2-3 months
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Related CAS #
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Synonym
UBP714; UBP-714; UBP 714.
IUPAC/Chemical Name
6-Bromo-4-methyl-2-oxo-2H-1-benzopyran-3-carboxylic acid
InChi Key
BWBWVUJRXNIUMA-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H7BrO4/c1-5-7-4-6(12)2-3-8(7)16-11(15)9(5)10(13)14/h2-4H,1H3,(H,13,14)
SMILES Code
O=C(C1=C(C)C2=CC(Br)=CC=C2OC1=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 283.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Irvine MW, Costa BM, Volianskis A, Fang G, Ceolin L, Collingridge GL, Monaghan DT, Jane DE. Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-D-aspartate receptors. Neurochem Int. 2012 Sep;61(4):593-600. doi: 10.1016/j.neuint.2011.12.020. Epub 2012 Jan 13. PubMed PMID: 22265875; PubMed Central PMCID: PMC3394894.