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MedKoo Cat#: 341112 | Name: Fluoroacetamide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fluoroacetamide is an organic compound based on acetamide with one fluorine atom replacing hydrogen on the methyl group.

Chemical Structure

Fluoroacetamide
Fluoroacetamide
CAS#640-19-7

Theoretical Analysis

MedKoo Cat#: 341112

Name: Fluoroacetamide

CAS#: 640-19-7

Chemical Formula: C2H4FNO

Exact Mass: 77.0277

Molecular Weight: 77.06

Elemental Analysis: C, 31.17; H, 5.23; F, 24.65; N, 18.18; O, 20.76

Price and Availability

Size Price Availability Quantity
1g USD 450.00 2 Weeks
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Related CAS #
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Synonym
Fluoroacetamide; 2-Fluoroacetamide; Monofluoroacetamide; α-Fluoroacetamide; NSC 31876; NSC31876; NSC-31876
IUPAC/Chemical Name
2-Fluoroacetamide
InChi Key
FVTWJXMFYOXOKK-UHFFFAOYSA-N
InChi Code
InChI=1S/C2H4FNO/c3-1-2(4)5/h1H2,(H2,4,5)
SMILES Code
NC(=O)CF
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 77.06 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Piva LC, De Marco JL, de Moraes LMP, Reis VCB, Torres FAG. Acetamidase as a dominant recyclable marker for Komagataella phaffii strain engineering. Appl Microbiol Biotechnol. 2018 Mar;102(6):2753-2761. doi: 10.1007/s00253-018-8824-9. Epub 2018 Feb 12. PubMed PMID: 29435619. 2: Wen W, Gao H, Kang N, Lu A, Qian C, Zhao Y. Treatment of severe fluoroacetamide poisoning in patient with combined multiple organ dysfunction syndrome by evidence-based integrated Chinese and Western medicines: A case report. Medicine (Baltimore). 2017 Jul;96(27):e7256. doi: 10.1097/MD.0000000000007256. PubMed PMID: 28682876; PubMed Central PMCID: PMC5502149. 3: SD + Fluoroacetamide Medium. Cold Spring Harb Protoc. 2017 Apr 3;2017(4):pdb.rec089540. doi: 10.1101/pdb.rec089540. PubMed PMID: 28373505. 4: Unione L, Alcalá M, Echeverria B, Serna S, Ardá A, Franconetti A, Cañada FJ, Diercks T, Reichardt N, Jiménez-Barbero J. Fluoroacetamide Moieties as NMR Spectroscopy Probes for the Molecular Recognition of GlcNAc-Containing Sugars: Modulation of the CH-π Stacking Interactions by Different Fluorination Patterns. Chemistry. 2017 Mar 17;23(16):3957-3965. doi: 10.1002/chem.201605573. Epub 2017 Feb 23. PubMed PMID: 28124793; PubMed Central PMCID: PMC5484281. 5: Kobayashi T, Hoppmann C, Yang B, Wang L. Using Protein-Confined Proximity To Determine Chemical Reactivity. J Am Chem Soc. 2016 Nov 16;138(45):14832-14835. Epub 2016 Nov 4. PubMed PMID: 27797495; PubMed Central PMCID: PMC5310709. 6: Wang R, Zhuo L, Wang Y, Ren L, Liu Q, Liu L. Lessons learned from poisoning cases caused by 2 illegal rodenticides: Tetramine and fluoroacetamide. Medicine (Baltimore). 2016 Oct;95(41):e5103. PubMed PMID: 27741126; PubMed Central PMCID: PMC5072953. 7: Cao F, Lu X, Hu X, Zhang Y, Zeng L, Chen L, Sun M. In vitro selection of DNA aptamers binding pesticide fluoroacetamide. Biosci Biotechnol Biochem. 2016 May;80(5):823-32. doi: 10.1080/09168451.2015.1136876. Epub 2016 Feb 12. PubMed PMID: 26873572. 8: Cooney TP, Varelis P, Bendall JG. High-Throughput Quantification of Monofluoroacetate (1080) in Milk as a Response to an Extortion Threat. J Food Prot. 2016 Feb;79(2):273-81. doi: 10.4315/0362-028X.JFP-15-405. PubMed PMID: 26818988. 9: Huang H, Huang X, Yu J. [Simultaneous determination of five hypertoxic rodenticides in serum by gas chromatography-mass spectrometry]. Se Pu. 2015 Mar;33(3):323-8. Chinese. PubMed PMID: 26182477. 10: Ge S, Arlow SI, Mormino MG, Hartwig JF. Pd-catalyzed α-arylation of trimethylsilyl enolates of α,α-difluoroacetamides. J Am Chem Soc. 2014 Oct 15;136(41):14401-4. doi: 10.1021/ja508590k. Epub 2014 Oct 3. PubMed PMID: 25254966; PubMed Central PMCID: PMC4210146. 11: Wang X, Gao H, Yao D, Tian Y, Su J, Zhang H, Sun C, Shi H. [Effect of acetamide on histopathology in cerebral cortex of rats with tetramine poisoning]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2014 Apr;32(4):289-92. Chinese. PubMed PMID: 24754949. 12: Kuklya A, Uteschil F, Kerpen K, Marks R, Telgheder U. Development of an electrospray-(63)Ni-differential ion mobility spectrometer for the analysis of aqueous samples. Talanta. 2014 Mar;120:173-80. doi: 10.1016/j.talanta.2013.10.056. Epub 2013 Dec 11. PubMed PMID: 24468357. 13: Luque de Castro MD, Delgado-Povedano MM. Ultrasound: a subexploited tool for sample preparation in metabolomics. Anal Chim Acta. 2014 Jan 2;806:74-84. doi: 10.1016/j.aca.2013.10.053. Epub 2013 Nov 7. Review. PubMed PMID: 24331041. 14: Seo YJ, Muench L, Reid A, Chen J, Kang Y, Hooker JM, Volkow ND, Fowler JS, Kim SW. Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brain. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6700-5. doi: 10.1016/j.bmcl.2013.10.038. Epub 2013 Oct 30. PubMed PMID: 24210501; PubMed Central PMCID: PMC4007514. 15: Zhang D, Zhang J, Zuo Z, Liao L. A retrospective analysis of data from toxic substance-related cases in Northeast China (Heilongjiang) between 2000 and 2010. Forensic Sci Int. 2013 Sep 10;231(1-3):172-7. doi: 10.1016/j.forsciint.2013.05.014. Epub 2013 Jun 7. PubMed PMID: 23890633. 16: Löser R, Fischer S, Hiller A, Köckerling M, Funke U, Maisonial A, Brust P, Steinbach J. Use of 3-[(18)F]fluoropropanesulfonyl chloride as a prosthetic agent for the radiolabelling of amines: Investigation of precursor molecules, labelling conditions and enzymatic stability of the corresponding sulfonamides. Beilstein J Org Chem. 2013 May 27;9:1002-11. doi: 10.3762/bjoc.9.115. Print 2013. PubMed PMID: 23766817; PubMed Central PMCID: PMC3678395. 17: Solis-Escalante D, Kuijpers NG, Bongaerts N, Bolat I, Bosman L, Pronk JT, Daran JM, Daran-Lapujade P. amdSYM, a new dominant recyclable marker cassette for Saccharomyces cerevisiae. FEMS Yeast Res. 2013 Feb;13(1):126-39. doi: 10.1111/1567-1364.12024. Epub 2012 Dec 17. PubMed PMID: 23253382; PubMed Central PMCID: PMC3563226. 18: Ettaoussi M, Sabaouni A, Rami M, Boutin JA, Delagrange P, Renard P, Spedding M, Caignard DH, Berthelot P, Yous S. Design, synthesis and pharmacological evaluation of new series of naphthalenic analogues as melatoninergic (MT1/MT2) and serotoninergic 5-HT2C dual ligands (I). Eur J Med Chem. 2012 Mar;49:310-23. doi: 10.1016/j.ejmech.2012.01.027. Epub 2012 Jan 20. PubMed PMID: 22301214. 19: Steiger MG, Vitikainen M, Uskonen P, Brunner K, Adam G, Pakula T, Penttilä M, Saloheimo M, Mach RL, Mach-Aigner AR. Transformation system for Hypocrea jecorina (Trichoderma reesei) that favors homologous integration and employs reusable bidirectionally selectable markers. Appl Environ Microbiol. 2011 Jan;77(1):114-21. doi: 10.1128/AEM.02100-10. Epub 2010 Nov 12. PubMed PMID: 21075888; PubMed Central PMCID: PMC3019734. 20: Ghosh AK, Banerjee S, Sinha S, Kang SB, Zajc B. Alpha-fluorovinyl Weinreb amides and alpha-fluoroenones from a common fluorinated building block. J Org Chem. 2009 May 15;74(10):3689-97. doi: 10.1021/jo802784w. PubMed PMID: 19361189; PubMed Central PMCID: PMC2817967.