PF-04781340 | CAS#1648726-56-0 | 5-HT2C receptor agonist

MedKoo Cat#: 562188 | Name: PF-04781340

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PF-04781340 is a potent, selective, and CNS penetrant 5-HT2C receptor agonist.

Chemical Structure

PF-04781340

CAS#1648726-56-0

Theoretical Analysis

MedKoo Cat#: 562188

Name: PF-04781340

CAS#: 1648726-56-0

Chemical Formula: C17H21N3

Exact Mass: 267.1735

Molecular Weight: 267.37

Elemental Analysis: C, 76.37; H, 7.92; N, 15.72

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

PF-04781340; PF 04781340; PF04781340;

IUPAC/Chemical Name

3-Benzyl-N-methyl-6,7,8,9-tetrahydro-5H-pyrido[3,4-d]azepin-1-amine

InChi Key

HFAURKSQTSLTBO-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H21N3/c1-18-17-16-8-10-19-9-7-14(16)12-15(20-17)11-13-5-3-2-4-6-13/h2-6,12,19H,7-11H2,1H3,(H,18,20)

SMILES Code

CNC1=NC(CC2=CC=CC=C2)=CC3=C1CCNCC3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 267.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Rouquet G, Moore DE, Spain M, Allwood DM, Battilocchio C, Blakemore DC, Fish PV, Jenkinson S, Jessiman AS, Ley SV, McMurray G, Storer RI. Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists. ACS Med Chem Lett. 2015 Jan 20;6(3):329-33. doi: 10.1021/ml500507v. eCollection 2015 Mar 12. PubMed PMID: 25815155; PubMed Central PMCID: PMC4360148.