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MedKoo Cat#: 341088 | Name: Y 26611

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Y 26611 is a biochemical.

Chemical Structure

Y 26611
Y 26611
CAS#143375-60-4

Theoretical Analysis

MedKoo Cat#: 341088

Name: Y 26611

CAS#: 143375-60-4

Chemical Formula: C18H19F2N3O4

Exact Mass: 379.1344

Molecular Weight: 379.36

Elemental Analysis: C, 56.99; H, 5.05; F, 10.02; N, 11.08; O, 16.87

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Y 26611; Y-26611; Y26611.
IUPAC/Chemical Name
Y 26611
InChi Key
MVKGRIHKSLEKTE-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H19F2N3O4/c19-13-5-11-15(14(20)16(13)22-3-4-27-10(6-21)7-22)23(9-1-2-9)8-12(17(11)24)18(25)26/h5,8-10H,1-4,6-7,21H2,(H,25,26)
SMILES Code
c1c2c(c(c(c1F)N3CCOC(C3)CN)F)n(cc(c2=O)C(=O)O)C4CC4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 379.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sakurai N, Sano M, Hirayama F, Kuroda T, Uemori S, Moriguchi A, Yamamoto K, Ikeda Y, Kawakita T. Synthesis and structure-activity relationships of 7-(2-aminoalkyl)morpholinoquinolones as anti-Helicobacter pylori agents. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2185-90. Erratum in: Bioorg Med Chem Lett 1998 Oct 20;8(20):2937. PubMed PMID: 9873510. 2: Akter U, Niwa M, Nose T, Kaida T, Matsuno H, Kozawa O, Uematsu T. Effects of several agents on UVB- and UVA plus systemic fluoroquinolone-induced erythema of guinea pig skin evaluated by reflectance colorimetry. Free Radic Biol Med. 1998 May;24(7-8):1113-9. PubMed PMID: 9626565. 3: Wada K, Saniabadi AR, Umemura K, Nakano M, Ito T, Nakashima M. Direct measurement of superoxide-dependent chemiluminescence from rat skin following UV-dependent fluoroquinolone-induced dermatitis. Free Radic Biol Med. 1995 May;18(5):923-7. PubMed PMID: 7797102. 4: Kubo S, Matsumoto T, Takahashi K, Haraoka M, Tanaka M, Sakumoto M, Sakamoto Y, Kumazawa J. Enhanced chemiluminescence response of polymorphonuclear leukocytes by new quinolone antimicrobials. Chemotherapy. 1994 Sep-Oct;40(5):333-6. PubMed PMID: 7956457. 5: Wada K, Saniabadi AR, Umemura K, Takiguchi Y, Nakashima M. UV-dependent quinolone-induced human erythrocyte membrane lipid peroxidation: studies on the phototoxicity of Y-26611, a new quinolone derivative. Pharmacol Toxicol. 1994 Apr-May;74(4-5):240-3. PubMed PMID: 8090693. 6: Araki K, Kuroda T, Uemori S, Moriguchi A, Ikeda Y, Hirayama F, Yokoyama Y, Iwao E, Yakushiji T. Quinolone antimicrobial agents substituted with morpholines at the 7-position. Syntheses and structure-activity relationships. J Med Chem. 1993 May 14;36(10):1356-63. PubMed PMID: 8388467. 7: Tomioka H, Sato K, Saito H. [Antimicrobial activity of new quinolones against Mycobacterium avium and Mycobacterium intracellulare determined by the dilution methods using 7H11 agar and Ogawa egg media]. Kekkaku. 1993 May;68(5):367-70. Japanese. PubMed PMID: 8331881. 8: Tomioka H, Sato K, Saito H, Ikeda Y. [Antimycobacterial activity of a newly synthesized fluoroquinolone, Y-26611]. Kekkaku. 1992 Jul;67(7):515-20. Japanese. PubMed PMID: 1331603.