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MedKoo Cat#: 341049 | Name: Propham
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Propham is a herbicide with suspected carcinogenic effects in humans.

Chemical Structure

Propham
Propham
CAS#122-42-9

Theoretical Analysis

MedKoo Cat#: 341049

Name: Propham

CAS#: 122-42-9

Chemical Formula: C10H13NO2

Exact Mass: 179.0946

Molecular Weight: 179.22

Elemental Analysis: C, 67.02; H, 7.31; N, 7.82; O, 17.85

Price and Availability

Size Price Availability Quantity
250mg USD 600.00
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Related CAS #
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Synonym
Propham; Isopropyl phenylcarbamate
IUPAC/Chemical Name
Carbamic acid, N-phenyl-, 1-methylethyl ester
InChi Key
VXPLXMJHHKHSOA-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H13NO2/c1-8(2)13-10(12)11-9-6-4-3-5-7-9/h3-8H,1-2H3,(H,11,12)
SMILES Code
c1(NC(=O)OC(C)C)ccccc1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 179.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wang F, Lin Y, Xu J, Wei F, Huang S, Wen S, Zhou H, Jiang Y, Wang H, Ling W, Li X, Yang X. Risk of papillary thyroid carcinoma and nodular goiter associated with exposure to semi-volatile organic compounds: A multi-pollutant assessment based on machine learning algorithms. Sci Total Environ. 2024 Mar 10;915:169962. doi: 10.1016/j.scitotenv.2024.169962. Epub 2024 Jan 14. PMID: 38219999. 2: Xie H, Li H, Zhao Y, Liu L, Chen X. Analysis of dietary exposure and risk assessment of pesticide residues in roots and rhizomes of Chinese herbs. J Food Sci. 2022 Jan;87(1):124-140. doi: 10.1111/1750-3841.15994. Epub 2021 Dec 22. PMID: 34939193. 3: Hlaing TS, Kondo H, Deguchi A, Miyoshi K. Induction of adventitious shoots and tetraploids in Antirrhinum majus L. by treatment of antimitotic agents in vitro without plant growth regulators. Plant Biotechnol (Tokyo). 2021 Mar 25;38(1):145-152. doi: 10.5511/plantbiotechnology.20.0731a. PMID: 34177334; PMCID: PMC8215452. 4: Wang D, Xu X, Zhang J, Zhao Y. Ligand Promoted Olefination of Anilides for Indirectly Introducing Fluorinated Functional Groups via Palladium Catalyst. J Org Chem. 2021 Feb 5;86(3):2696-2705. doi: 10.1021/acs.joc.0c02701. Epub 2021 Jan 27. PMID: 33502195. 5: Bodur S, Özlü C, Tışlı B, Fırat M, Chormey DS, Bakırdere S. Analytical protocol for determination of endosulfan beta, propham, chlorpyrifos, and acibenzolar-s-methyl in lake water and wastewater samples by gas chromatography- mass spectrometry after dispersive liquid-liquid microextraction. Environ Monit Assess. 2020 Mar 28;192(4):253. doi: 10.1007/s10661-020-8214-5. PMID: 32222945. 6: Zhang L, Hang P, Zhou X, Dai C, He Z, Jiang J. Mineralization of the herbicide swep by a two-strain consortium and characterization of a new amidase for hydrolyzing swep. Microb Cell Fact. 2020 Jan 7;19(1):4. doi: 10.1186/s12934-020-1276-9. PMID: 31910844; PMCID: PMC6945715. 7: Piel C, Pouchieu C, Carles C, Béziat B, Boulanger M, Bureau M, Busson A, Grüber A, Lecluse Y, Migault L, Renier M, Rondeau V, Schwall X, Tual S; AGRICAN group; Pierre L, Baldi I. Agricultural exposures to carbamate herbicides and fungicides and central nervous system tumour incidence in the cohort AGRICAN. Environ Int. 2019 Sep;130:104876. doi: 10.1016/j.envint.2019.05.070. Epub 2019 Jul 22. PMID: 31344646. 8: Sun L, Gao X, Chen W, Huang K, Bai N, Lyu W, Liu H. Characterization of the Propham Biodegradation Pathway in Starkeya sp. Strain YW6 and Cloning of a Novel Amidase Gene mmH. J Agric Food Chem. 2019 Apr 17;67(15):4193-4199. doi: 10.1021/acs.jafc.8b06928. Epub 2019 Apr 8. PMID: 30864436. 9: Özcan A, Gürbüz M, Özcan AA. Preparation of a disposable and low-cost electrochemical sensor for propham detection based on over-oxidized poly(thiophene) modified pencil graphite electrode. Talanta. 2018 Sep 1;187:125-132. doi: 10.1016/j.talanta.2018.05.018. Epub 2018 May 7. PMID: 29853024. 10: Yabalak E, Görmez Ö, Gizir AM. Subcritical water oxidation of propham by H2O2 using response surface methodology (RSM). J Environ Sci Health B. 2018 May 4;53(5):334-339. doi: 10.1080/03601234.2018.1431468. Epub 2018 Feb 12. PMID: 29431600. 11: González-Martín MI, Revilla I, Vivar-Quintana AM, Betances Salcedo EV. Pesticide residues in propolis from Spain and Chile. An approach using near infrared spectroscopy. Talanta. 2017 Apr 1;165:533-539. doi: 10.1016/j.talanta.2016.12.061. Epub 2017 Jan 4. PMID: 28153295. 12: Allinson M, Kageyama S, Nakajima D, Kamata R, Shiraishi F, Goto S, Salzman SA, Allinson G. A pilot survey of 39 Victorian WWTP effluents using a high speed luminescent umu test in conjunction with a novel GC-MS-database technique for automatic identification of micropollutants. Water Sci Technol. 2012;66(4):768-74. doi: 10.2166/wst.2012.242. PMID: 22766865. 13: Zhang J, Yin JG, Hang BJ, Cai S, He J, Zhou SG, Li SP. Cloning of a novel arylamidase gene from Paracoccus sp. strain FLN-7 that hydrolyzes amide pesticides. Appl Environ Microbiol. 2012 Jul;78(14):4848-55. doi: 10.1128/AEM.00320-12. Epub 2012 Apr 27. PMID: 22544249; PMCID: PMC3416369. 14: Huang J, Kong X, Yao B, He Q, Hao K. [Determination of 88 pesticide residues in cranberry plant extract by gas chromatography-triple quadrupole tandem mass spectrometry]. Se Pu. 2011 Oct;29(10):974-82. Chinese. PMID: 22268353. 15: Ozcan A, Sahin Y, Oturan MA. Removal of propham from water by using electro- Fenton technology: kinetics and mechanism. Chemosphere. 2008 Oct;73(5):737-44. doi: 10.1016/j.chemosphere.2008.06.027. Epub 2008 Jul 27. PMID: 18664400. 16: Ozcan A, Sahin Y, Koparal AS, Oturan MA. Propham mineralization in aqueous medium by anodic oxidation using boron-doped diamond anode: influence of experimental parameters on degradation kinetics and mineralization efficiency. Water Res. 2008 Jun;42(12):2889-98. doi: 10.1016/j.watres.2008.02.027. Epub 2008 Mar 4. PMID: 18377944. 17: Yemets A, Stelmakh O, Blume YB. Effects of the herbicide isopropyl-N-phenyl carbamate on microtubules and MTOCs in lines of Nicotiana sylvestris resistant and sensitive to its action. Cell Biol Int. 2008 Jun;32(6):623-9. doi: 10.1016/j.cellbi.2008.01.012. Epub 2008 Jan 25. PMID: 18343166. 18: Weiss Y, Rubin B, Shulman A, Ben Shir I, Keinan E, Wolf S. Determination of plant resistance to carbamate herbicidal compounds inhibiting cell division and early growth by seed and plantlets bioassays. Nat Protoc. 2006;1(5):2282-7. doi: 10.1038/nprot.2006.380. PMID: 17406469. 19: Arribas AS, Bermejo E, Chicharro M, Zapardiel A. Application of matrix solid-phase dispersion to the propham and maleic hydrazide determination in potatoes by differential pulse voltammetry and HPLC. Talanta. 2007 Jan 15;71(1):430-6. doi: 10.1016/j.talanta.2006.04.019. Epub 2006 May 23. PMID: 19071323. 20: Kolkenbrock S, Parschat K, Beermann B, Hinz HJ, Fetzner S. N-acetylanthranilate amidase from Arthrobacter nitroguajacolicus Rü61a, an alpha/beta-hydrolase-fold protein active towards aryl-acylamides and -esters, and properties of its cysteine-deficient variant. J Bacteriol. 2006 Dec;188(24):8430-40. doi: 10.1128/JB.01085-06. Epub 2006 Oct 13. Erratum in: J Bacteriol. 2007 May;189(10):3933. PMID: 17041061; PMCID: PMC1698245.