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MedKoo Cat#: 562080 | Name: MV1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MV1 is a SMAC mimic that acts as an IAP antagonist.

Chemical Structure

MV1
MV1
CAS#1001600-54-9

Theoretical Analysis

MedKoo Cat#: 562080

Name: MV1

CAS#: 1001600-54-9

Chemical Formula: C33H44N4O5

Exact Mass: 576.3312

Molecular Weight: 576.73

Elemental Analysis: C, 68.72; H, 7.69; N, 9.71; O, 13.87

Price and Availability

Size Price Availability Quantity
5mg USD 190.00 Ready to ship
10mg USD 350.00 Ready to ship
25mg USD 550.00 Ready to ship
50mg USD 950.00 Ready to ship
100mg USD 1,450.00 Ready to ship
200mg USD 2,450.00 Ready to ship
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Related CAS #
No Data
Synonym
MV1; MV-1; MV 1;
IUPAC/Chemical Name
methyl (S)-2-((S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoate
InChi Key
UUPZYAHONNHULX-CJBSCAABSA-N
InChi Code
InChI=1S/C33H44N4O5/c1-22(34-2)30(38)35-28(25-18-11-6-12-19-25)32(40)37-21-13-20-26(37)31(39)36-29(33(41)42-3)27(23-14-7-4-8-15-23)24-16-9-5-10-17-24/h4-5,7-10,14-17,22,25-29,34H,6,11-13,18-21H2,1-3H3,(H,35,38)(H,36,39)/t22-,26-,28-,29-/m0/s1
SMILES Code
O=C(OC)[C@@H](NC([C@H]1N(C([C@H](C2CCCCC2)NC([C@@H](NC)C)=O)=O)CCC1)=O)C(C3=CC=CC=C3)C4=CC=CC=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
Soluble in DMSO 125.0 216.70
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 576.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Tomoshige S, Nomura S, Ohgane K, Hashimoto Y, Ishikawa M. Degradation of huntingtin mediated by a hybrid molecule composed of IAP antagonist linked to phenyldiazenyl benzothiazole derivative. Bioorg Med Chem Lett. 2018 Jan 12. pii: S0960-894X(18)30025-8. doi: 10.1016/j.bmcl.2018.01.012. [Epub ahead of print] PubMed PMID: 29366651. 2: Tomoshige S, Hashimoto Y, Ishikawa M. Efficient protein knockdown of HaloTag-fused proteins using hybrid molecules consisting of IAP antagonist and HaloTag ligand. Bioorg Med Chem. 2016 Jul 15;24(14):3144-8. doi: 10.1016/j.bmc.2016.05.035. Epub 2016 May 20. PubMed PMID: 27236416.