MedKoo Cat#: 341034 | Name: Mebanazine oxalate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mebanazine oxalate

Chemical Structure

Mebanazine oxalate
Mebanazine oxalate
CAS#34675-74-6

Theoretical Analysis

MedKoo Cat#: 341034

Name: Mebanazine oxalate

CAS#: 34675-74-6

Chemical Formula: C10H14N2O4

Exact Mass: 226.0954

Molecular Weight: 226.23

Elemental Analysis: C, 53.09; H, 6.24; N, 12.38; O, 28.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Mebanazine oxalate; Z-87.
IUPAC/Chemical Name
Hydrazine, (1-phenylethyl)-, ethanedioate (1:1)
InChi Key
ZJHCOEKEFDUTPX-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H12N2.C2H2O4/c1-7(10-9)8-5-3-2-4-6-8;3-1(4)2(5)6/h2-7,10H,9H2,1H3;(H,3,4)(H,5,6)
SMILES Code
CC(c1ccccc1)NN.C(=O)(C(=O)O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 226.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Garcha G, Imrie PR, Marley E, Thomas DV. [14C]-beta-phenethylamine, its distribution after administration by various routes to cats, and the effects of monoamine oxidase inhibitors. Br J Pharmacol. 1985 Dec;86(4):877-88. PubMed PMID: 4075021; PubMed Central PMCID: PMC1916635. 2: Szadowska A, Mazur M, Szmigielski A, Szmigielska H, Winer A. [Heterocyclic amine derivatives - analogs of mebanazine, pheniprazine and phenelzine. II. Studies on the effect, on the central nervous system, of derivatives of perhydroazepine, perhydro-1,4-diazepine, perhydro-1,4-oxazepine, perhydro-1,5-oxazocine and morpholine-containing arylalkyloamine groups]. Acta Pol Pharm. 1983;40(1):111-8. Polish. PubMed PMID: 6136156. 3: Koc BA, Marley E. Antipodal central effects of apomorphine and dopamine in chickens. Neuropharmacology. 1982 Mar;21(3):249-60. PubMed PMID: 6803186. 4: Brambilla G, Cavanna M, Faggin P, Pino A, Robbiano L, Bennicelli C, Zanacchi P, Camoirano A, De Flora S. Genotoxic activity of five antidepressant hydrazines in a battery of in vivo and in vitro short-term tests. J Toxicol Environ Health. 1982 Feb;9(2):287-303. PubMed PMID: 7042990. 5: de Flora S. A "spiral test" applied to bacterial mutagenesis assays. Mutat Res. 1981 Jul;82(2):213-27. PubMed PMID: 7022176. 6: Parodi S, De Flora S, Cavanna M, Pino A, Robbiano L, Bennicelli C, Brambilla G. DNA-damaging activity in vivo and bacterial mutagenicity of sixteen hydrazine derivatives as related quantitatively to their carcinogenicity. Cancer Res. 1981 Apr;41(4):1469-82. PubMed PMID: 7214329. 7: Al-Ubaidi F, Bakhle YS. Metabolism of vasoactive hormones in human isolated lung. Clin Sci (Lond). 1980 Jan;58(1):45-51. PubMed PMID: 7353353. 8: Bolton GC, Griffiths LA. The metabolic disposition of [14C]pivhydrazine, [14C]mebanazine, and [14C]benzylhydrazine in the rat. Drug Metab Dispos. 1979 Nov-Dec;7(6):388-92. PubMed PMID: 43225. 9: Gargiulo G, Nisticò G. Time course of 5,6-dihydroxytryptamine neurotoxic effects on fowl diencephalon and upper brain stem monoaminergic pathways. J Anat. 1978 Jun;126(Pt 2):261-74. PubMed PMID: 670063; PubMed Central PMCID: PMC1235687. 10: Cox B, Kastin AJ, Schnieden H. A comparison between a melanocyte-stimulating hormone inhibitory factor (MIF-I) and substances known to activate central dopamine receptors. Eur J Pharmacol. 1976 Mar;36(1):141-7. PubMed PMID: 4332. 11: Marley E, Nistiò G. Tryptamines and some other substances affecting waking and sleep in fowls. Br J Pharmacol. 1975 Feb;53(2):193-205. PubMed PMID: 1148481; PubMed Central PMCID: PMC1666283. 12: Cox B, Tha SJ. Amantadin e tremor, a 5-hydroxytryptamine-mediated response? Eur J Pharmacol. 1975 Feb;30(2):344-51. PubMed PMID: 123858. 13: Marley E, Nistico G. Effects of catecholamines and adenosine derivatives given into the brain of fowls. Br J Pharmacol. 1972 Dec;46(4):619-36. PubMed PMID: 4347707; PubMed Central PMCID: PMC1666373. 14: Clark B, Thompson JW, Widdrington G. Analysis of the inhibition of pethidine N-demethylation by monoamine oxidase inhibitors and some other drugs with special reference to drug interactions in man. Br J Pharmacol. 1972 Jan;44(1):89-99. PubMed PMID: 4401309; PubMed Central PMCID: PMC1665689. 15: Frohman LA. Stimulation of insulin secretion in rats by pargyline and mebanazine. Diabetes. 1971 May;20(5):266-70. PubMed PMID: 5581314. 16: Alabaster VA, Bakhle YS. Removal of 5-hydroxytryptamine in the pulmonary circulation of rat isolated lungs. Br J Pharmacol. 1970 Nov;40(3):468-82. PubMed PMID: 5497795; PubMed Central PMCID: PMC1703190. 17: Barrett AM. The mode of action of insulin potentiation by mebanazine. J Pharm Pharmacol. 1970 Apr;22(4):291-7. PubMed PMID: 4392571. 18: Barrett AM. Simulation of the apparent effects of mebanazine on growth hormone by pair-feeding of control animals. J Pharm Pharmacol. 1969 Aug;21(8):481-7. PubMed PMID: 4389709. 19: Barrett AM, Cullum VA. Lack of inter-action between propranolol and mebanazine. J Pharm Pharmacol. 1968 Dec;20(12):911-5. PubMed PMID: 4388330. 20: Collier HO, James GW, Piper PJ. Antagonism by fenamates and like-acting drugs of bronchoconstriction induced by bradykinin or antigen in the guinea-pig. Br J Pharmacol. 1968 Sep;34(1):76-87. PubMed PMID: 5676040; PubMed Central PMCID: PMC1703405.