MedKoo Cat#: 341032 | Name: Riligustilide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Riligustilide is a nonsteroidal phytoprogestogen that is found in Ligusticum chuanxiong.

Chemical Structure

Riligustilide
Riligustilide
CAS#89354-45-0

Theoretical Analysis

MedKoo Cat#: 341032

Name: Riligustilide

CAS#: 89354-45-0

Chemical Formula: C24H28O4

Exact Mass: 380.1988

Molecular Weight: 380.48

Elemental Analysis: C, 75.76; H, 7.42; O, 16.82

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Riligustilide
IUPAC/Chemical Name
Z-6.8',7.3'-Diligustilide
InChi Key
TYSOMZQRYGBSKN-ZGQZQFGGSA-N
InChi Code
InChI=1S/C24H28O4/c1-3-5-11-19-16-13-12-14-17(8-4-2)24(21(14)20(16)23(26)27-19)18-10-7-6-9-15(18)22(25)28-24/h6,9,11,14,17,21H,3-5,7-8,10,12-13H2,1-2H3/b19-11-/t14-,17-,21+,24+/m1/s1
SMILES Code
O1C(C=2[C@H]3[C@@]4(C5=C(C(O4)=O)C=CCC5)[C@H](CCC)[C@H]3CCC2\C1=C\CCC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 380.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gong W, Zhou Y, Li X, Gao X, Tian J, Qin X, Du G. Neuroprotective and Cytotoxic Phthalides from Angelicae Sinensis Radix. Molecules. 2016 Apr 26;21(5). pii: E549. doi: 10.3390/molecules21050549. PubMed PMID: 27128890. 2: Duan SM, Xu J, Bai YJ, Ding Y, Kong M, Liu HH, Li XY, Zhang QS, Chen HB, Liu LF, Li SL. Sulfur dioxide residue in sulfur-fumigated edible herbs: The fewer, the safer? Food Chem. 2016 Feb 1;192:119-24. doi: 10.1016/j.foodchem.2015.07.003. Epub 2015 Jul 3. PubMed PMID: 26304328. 3: Hu LC, Wu X, Yang XD. [Optimization of supercritical fluid extraction of bioactive components in Ligusticum chuanxiong by orthogonal array design]. Zhongguo Zhong Yao Za Zhi. 2013 Oct;38(20):3484-8. Chinese. PubMed PMID: 24490558. 4: Wang J, Yang JB, Wang AG, Ji TF, Su YL. [Studies on the chemical constituents of Ligusticum sinense]. Zhong Yao Cai. 2011 Mar;34(3):378-80. Chinese. PubMed PMID: 21823452. 5: León A, Toscano RA, Tortoriello J, Delgado G. Phthalides and other constituents from Ligusticum porteri; sedative and spasmolytic activities of some natural products and derivatives. Nat Prod Res. 2011 Aug;25(13):1234-42. doi: 10.1080/14786419.2010.534735. Epub 2011 Jul 28. PubMed PMID: 21797735. 6: León A, Chávez MI, Delgado G. (1)H and DOSY NMR spectroscopy analysis of Ligusticum porteri rhizome extracts. Magn Reson Chem. 2011 Aug;49(8):469-76. doi: 10.1002/mrc.2767. Epub 2011 Jul 14. PubMed PMID: 21761449. 7: Li SL, Yan R, Tam YK, Lin G. Post-harvest alteration of the main chemical ingredients in Ligusticum chuanxiong Hort. (Rhizoma Chuanxiong). Chem Pharm Bull (Tokyo). 2007 Jan;55(1):140-4. PubMed PMID: 17202719. 8: Deng S, Chen SN, Lu J, Wang ZJ, Nikolic D, van Breemen RB, Santarsiero BD, Mesecar A, Fong HH, Farnsworth NR, Pauli GF. GABAergic phthalide dimers from Angelica sinensis (Oliv.) Diels. Phytochem Anal. 2006 Nov-Dec;17(6):398-405. PubMed PMID: 17144247. 9: Lim LS, Shen P, Gong YH, Yong EL. Dimeric progestins from rhizomes of Ligusticum chuanxiong. Phytochemistry. 2006 Apr;67(7):728-34. Epub 2006 Mar 3. PubMed PMID: 16516938. 10: Li SL, Lin G, Chung HS, Tam YK. [Study on fingerprint of rhizoma chuanxiong by HPLC-DAD-MS]. Yao Xue Xue Bao. 2004 Aug;39(8):621-6. Chinese. PubMed PMID: 15563065. 11: Li SL, Chan SS, Lin G, Ling L, Yan R, Chung HS, Tam YK. Simultaneous analysis of seventeen chemical ingredients of Ligusticum chuanxiong by on-line high performance liquid chromatography-diode array detector-mass spectrometry. Planta Med. 2003 May;69(5):445-51. PubMed PMID: 12802727.