CRT0093964 | CAS#700856-05-9 | AKR1C3 inhibitor

MedKoo Cat#: 562038 | Name: CRT0093964

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CRT0093964 is a selective inhibitor of AKR1C3.

Chemical Structure

CRT0093964

CAS#700856-05-9

Theoretical Analysis

MedKoo Cat#: 562038

Name: CRT0093964

CAS#: 700856-05-9

Chemical Formula: C15H20ClN3O2

Exact Mass: 309.1244

Molecular Weight: 309.79

Elemental Analysis: C, 58.16; H, 6.51; Cl, 11.44; N, 13.56; O, 10.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

CRT0093964; CRT-0093964; CRT 0093964;

IUPAC/Chemical Name

[4-(4-Chloro-phenyl)-piperazin-1-yl]-morpholin-4-yl-methanone

InChi Key

KDSIRFZJOTZBPT-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H20ClN3O2/c16-13-1-3-14(4-2-13)17-5-7-18(8-6-17)15(20)19-9-11-21-12-10-19/h1-4H,5-12H2

SMILES Code

O=C(N1CCN(C2=CC=C(Cl)C=C2)CC1)N3CCOCC3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 309.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Selective AKR1C3 inhibitors do not recapitulate the anti-leukaemic activities of the pan-AKR1C inhibitor medroxyprogesterone acetate. F Khanim, N Davies, P Veliça, R Hayden, J Ride, C Pararasa, M G Chong, U Gunther, N Veerapen, P Winn, R Farmer, E Trivier, L Rigoreau, M Drayson & C Bunce. British Journal of Cancer volume 110, pages 1506–1516 (18 March 2014) doi:10.1038/bjc.2014.83.