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MedKoo Cat#: 341018 | Name: Piprozoline

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Piprozoline(or piprozolin) is a medication for bile therapy.

Chemical Structure

Piprozoline
Piprozoline
CAS#63250-48-6

Theoretical Analysis

MedKoo Cat#: 341018

Name: Piprozoline

CAS#: 63250-48-6

Chemical Formula: C14H22N2O3S

Exact Mass: 298.1351

Molecular Weight: 298.40

Elemental Analysis: C, 56.35; H, 7.43; N, 9.39; O, 16.08; S, 10.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Piprozoline; piprozolin.
IUPAC/Chemical Name
delta(sup 2,alpha)-Thiazolidineacetic acid, 3-ethyl-4-oxo-5-piperidino-, ethyl ester, (Z)-
InChi Key
UAXYBJSAPFTPNB-BMSUMIBZSA-N
InChi Code
InChI=1S/C14H22N2O3S/c1-3-16-11(10-12(17)19-4-2)20-14(13(16)18)15-8-6-5-7-9-15/h10,14H,3-9H2,1-2H3/b11-10-/t14-/m0/s1
SMILES Code
C(\C=C1/S[C@@H](C(N1CC)=O)N1CCCCC1)(=O)OCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 298.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chankvetadze B. Enantioseparation in capillary chromatography and capillary electrochromatography using polysaccharide-type chiral stationary phases. Methods Mol Biol. 2004;243:387-399. PubMed PMID: 14970638. 2: Tiscornia OM, Cresta MA, Tumilasci O, Waisman H. [Hydroelactic and ecbolic of piprozoline on basal bile-pancreatic secretion in rats]. Acta Gastroenterol Latinoam. 1984;14(1):13-25. Spanish. PubMed PMID: 6524268. 3: Satzinger G. [Structure-activity relationships of etozolin, a novel diuretic (author's transl)]. Arzneimittelforschung. 1977;27(9a):1742-45. German. PubMed PMID: 578762. 4: Friedrich G, Vollmer KO. [Studies on the influence of piprozoline on the microsomal enzyme system of the rat liver (author's transl)]. Arzneimittelforschung. 1977;27(2b):517-9. German. PubMed PMID: 577415. 5: Gladigau V, Ehret I. [Metabolism and pharmacokinetics of piprozoline in rat, dog and man. 3rd communication: Determination of piprozoline and metabolite I in plasma and urine (author's transl)]. Arzneimittelforschung. 1977;27(2b):512-6. German. PubMed PMID: 577414. 6: Hodenberg AV, Klemisch W, Vollmer KO. [Metabolism and pharmacokinetics of piprozoline in rat, dog and man. 2nd Communication: Determination of metabolic profiles with the aid of an HPLC-radioactivity detection system following direct injection of urine and bile onto a reversed-phase column (author's transl)]. Arzneimittelforschung. 1977;27(2b):508-11. German. PubMed PMID: 577413. 7: Vollmer KO, Hodenberg AV, Poisson A, Bode R, Schauerte E. [Metabolism and pharmacokinetics of piprozoline in the rat, dog and man. 1. Studies with the radioactively-labeled substance]. Arzneimittelforschung. 1977;27(2b):502-8. German. PubMed PMID: 577412. 8: Gladigau V, Ehret I, Hengy H. [TLC-method for quantitative densitometric determination of piprozoline and its main metabolite using internal standards (author's transl)]. Arzneimittelforschung. 1977;27(2b):499-502. German. PubMed PMID: 577411. 9: Wiegleb J, Herrmann M, Leuschner F. [Toxicological study on piprozoline (author's transl)]. Arzneimittelforschung. 1977;27(2b):493-9. German. PubMed PMID: 577410. 10: Tauschel HD, Hermann M. [Pharmacological effect of piprozoline on the exocrine pancreas of dogs (author's transl)]. Arzneimittelforschung. 1977;27(2b):489-93. German. PubMed PMID: 577409. 11: Tauschel HD, Herrmann M. [Pharmacological effects of piprozoline on bile secretion in dogs (author's transl)]. Arzneimittelforschung. 1977;27(2b):480-8. German. PubMed PMID: 577408. 12: Herrmann M, Bierkenmayer E, Ganser V, Heldt W, Steinbrecher W. [On the pharmacology of piprozoline (author's transl)]. Arzneimittelforschung. 1977;27(2b):467-75. German. PubMed PMID: 577406. 13: Satzinger G. [2-Carbethoxymethylene-thiazolidones-(4), a novel series of Heterocycles with choleretic properties]. Arzneimittelforschung. 1977;27(2b):463-6. German. PubMed PMID: 577405. 14: Schleicher E. [Piprozoline in clinical trials (author's transl)]. Arzneimittelforschung. 1977;27(2b):520-6. German. PubMed PMID: 326261.