DNS-0056 is a thienotriazolopyrimidinone phosphodiesterase-1 (PDE1) inhibitor with IC50=25 nM. It has good pharmacokinetic properties. It has been shown in rat models to penetrate the brain to significantly increase long-term recognition memory without altering exploratory behavior.
MedKoo Cat#: 571490
Name: DNS-0056
CAS#: 1513844-19
Chemical Formula: C24H26FN5O3S
Exact Mass: 483.1740
Molecular Weight: 483.56
Elemental Analysis: C, 59.61; H, 5.42; F, 3.93; N, 14.48; O, 9.93; S, 6.63
The following data is based on the product molecular weight 483.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |