p18SMI-22 | CAS#1043924-66-8 | INK4C inhibitor

MedKoo Cat#: 527690 | Name: p18SMI-22

Description:

WARNING: This product is for research use only, not for human or veterinary use.

p18SMI-22 is a novel INK4C inhibitor, specifically blocking the bioactivity of p18 protein.

Chemical Structure

p18SMI-22

CAS#1043924-66-8

Theoretical Analysis

MedKoo Cat#: 527690

Name: p18SMI-22

CAS#: 1043924-66-8

Chemical Formula: C17H18N2O5S

Exact Mass: 362.0936

Molecular Weight: 362.40

Elemental Analysis: C, 56.34; H, 5.01; N, 7.73; O, 22.07; S, 8.85

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

p18SMI22; p18SMI 22; p18SMI-22

IUPAC/Chemical Name

Methyl (R)-(4-Acetylamino-benzenesulfonylamino)-phenyl-acetate

InChi Key

YUIQPNUBSVAFPL-MRXNPFEDSA-N

InChi Code

InChI=1S/C17H18N2O5S/c1-12(20)18-14-8-10-15(11-9-14)25(22,23)19-16(17(21)24-2)13-6-4-3-5-7-13/h3-11,16,19H,1-2H3,(H,18,20)/t16-/m1/s1

SMILES Code

O=C(OC)[C@H](NS(=O)(C1=CC=C(NC(C)=O)C=C1)=O)C2=CC=CC=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 362.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ardenne M, Reitnauer PG. [Demonstration of tumor inhibiting properties of a strongly immunostimulating low-molecular weight substance. Comparative studies with ifosfamide on the immuno-labile DS carcinosarcoma. Stimulation of the autoimmune activity for approx. 20 days by BA 1, a N-(2-cyanoethylene)-urea. Novel prophylactic possibilities]. Arzneimittelforschung. 1975 Sep;25(9):1369-79. German. PubMed PMID: 22.