MedKoo Cat#: 561866 | Name: Tricaprilin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tricaprilin, also known as Glyceryl trioctanoate, is a triglyceride drug candidate.

Chemical Structure

Tricaprilin
Tricaprilin
CAS#538-23-8

Theoretical Analysis

MedKoo Cat#: 561866

Name: Tricaprilin

CAS#: 538-23-8

Chemical Formula: C27H50O6

Exact Mass: 470.3607

Molecular Weight: 470.69

Elemental Analysis: C, 68.90; H, 10.71; O, 20.39

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Synonym
Tricaprilin; trioctanoin; tricaprylic glyceride; tricaprylin, Glyceryl trioctanoate
IUPAC/Chemical Name
propane-1,2,3-triyl trioctanoate
InChi Key
VLPFTAMPNXLGLX-UHFFFAOYSA-N
InChi Code
InChI=1S/C27H50O6/c1-4-7-10-13-16-19-25(28)31-22-24(33-27(30)21-18-15-12-9-6-3)23-32-26(29)20-17-14-11-8-5-2/h24H,4-23H2,1-3H3
SMILES Code
CCCCCCCC(OCC(OC(CCCCCCC)=O)COC(CCCCCCC)=O)=O
Appearance
Liquid
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Physical State : Liquid Storage : Store at 4° C Melting Point : 9° C Boiling Point : 233° C at 1 mmHg Density : .96 g/cm3 at 20° C

Preparing Stock Solutions

The following data is based on the product molecular weight 470.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: More SB, Waghmare JT, Gogate PR. Ultrasound pretreatment as a novel approach for intensification of lipase catalyzed esterification of tricaprylin. Ultrason Sonochem. 2017 May;36:253-261. doi: 10.1016/j.ultsonch.2016.11.036. Epub 2016 Nov 29. PubMed PMID: 28069208. 2: Kolev V, Ivanova A, Madjarova G, Aserin A, Garti N. Unit cell structure of water-filled monoolein in inverted hexagonal mesophase in the presence of incorporated tricaprylin and entrapped lysozyme. Eur Biophys J. 2016 Mar;45(2):99-112. doi: 10.1007/s00249-015-1080-3. Epub 2015 Sep 30. PubMed PMID: 26424533. 3: Liu N, Shi J, Xiao Y, Yasue M, Takei Y, Sanefuji H, Tsujimoto G, Hirasawa A. Effects of a Tricaprylin Emulsion on Anti-glomerular Basement Membrane Glomerulonephritis in Rats: In Vivo and in Silico Studies. Biol Pharm Bull. 2015;38(8):1175-84. doi: 10.1248/bpb.b15-00124. PubMed PMID: 26235580. 4: Camacho-Ruiz Mde L, Mateos-Díaz JC, Carrière F, Rodriguez JA. A broad pH range indicator-based spectrophotometric assay for true lipases using tributyrin and tricaprylin. J Lipid Res. 2015 May;56(5):1057-67. doi: 10.1194/jlr.D052837. Epub 2015 Mar 7. PubMed PMID: 25748441; PubMed Central PMCID: PMC4409282.