MedKoo Cat#: 581066 | Name: S-KKWK

Description:

WARNING: This product is for research use only, not for human or veterinary use.

S-KKWK is potent influenza A virus entry inhibitors targeting a conserved region of hemagglutinin.The anti-IAV test indicated that S-KKWK and its derivatives displayed potent antiviral activities against a broad variety of influenza A viral strains including oseltamivir-resistant strains and clinically relevant isolates with IC50 values ranging from 0.7 to 3.0µM. S-KKWK and its derivatives are prospective candidates for potent antivirals.

Chemical Structure

S-KKWK
S-KKWK
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 581066

Name: S-KKWK

CAS#: N/A

Chemical Formula: C58H95N9O6

Exact Mass:

Molecular Weight: 1014.46

Elemental Analysis:

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
S-KKWK; Cholesterol -KKWK conjugate
IUPAC/Chemical Name
Cholesterol-Gly-Lys-Lys-Trp-Lys-NH2
InChi Key
InChi Code
SMILES Code
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,014.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lin D, Luo Y, Yang G, Li F, Xie X, Chen D, He L, Wang J, Ye C, Lu S, Lv L, Liu S, He J. Potent influenza A virus entry inhibitors targeting a conserved region of hemagglutinin. Biochem Pharmacol. 2017 Nov 15;144:35-51. doi: 10.1016/j.bcp.2017.07.023. Epub 2017 Aug 1. PubMed PMID: 28774731.