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MedKoo Cat#: 555133 | Name: Dansylamide
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dansylamide is a reactive fluorescent dye that is used in biochemistry and chemistry to label substances with the fluorescent dansyl group. It is also produced as a side-product in the labelling of amino acids with dansyl chloride.

Chemical Structure

Dansylamide
Dansylamide
CAS#1431-39-6

Theoretical Analysis

MedKoo Cat#: 555133

Name: Dansylamide

CAS#: 1431-39-6

Chemical Formula: C12H14N2O2S

Exact Mass: 250.0776

Molecular Weight: 250.32

Elemental Analysis: C, 57.58; H, 5.64; N, 11.19; O, 12.78; S, 12.81

Price and Availability

Size Price Availability Quantity
250mg USD 250.00 2 Weeks
1g USD 550.00 2 Weeks
5g USD 950.00 2 Weeks
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Related CAS #
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Synonym
Dansylamide; DNSA; Dansyl amide;
IUPAC/Chemical Name
5-Dimethylaminonaphthalene-1-sulfonamide
InChi Key
TYNBFJJKZPTRKS-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H14N2O2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3,(H2,13,15,16)
SMILES Code
O=S(C1=C2C=CC=C(N(C)C)C2=CC=C1)(N)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 250.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Tripathi AK. A Fluorescence Study on Binding Interaction of N-acetylated Dansylamide Conjugates with β-cyclodextrin, Tween-20 and DPPC Lipid Bilayer Membrane. J Fluoresc. 2017 Dec 26. doi: 10.1007/s10895-017-2202-3. [Epub ahead of print] PubMed PMID: 29277860. 2: Yang H, Huang Y, Liu J, Tang P, Sun Q, Xiong X, Tang B, He J, Li H. Binding modes of environmental endocrine disruptors to human serum albumin: insights from STD-NMR, ITC, spectroscopic and molecular docking studies. Sci Rep. 2017 Sep 11;7(1):11126. doi: 10.1038/s41598-017-11604-3. PubMed PMID: 28894220; PubMed Central PMCID: PMC5593971. 3: Devadasan C, Starr B, Doyle KM. Effect of N1-dansylspermine and Ro25,6981 on locomotor activity in naive mice and in the reserpinized mouse model of Parkinson's disease. Neuroreport. 2016 Dec 7;27(17):1243-1247. PubMed PMID: 27653937. 4: Tripathi AK, Mohapatra M, Mishra AK. Fluorescence of N-acylated dansylamide with a long hydrophobic tail: sensitive response to premicellar aggregation of sodium deoxycholate. Phys Chem Chem Phys. 2015 Nov 28;17(44):29985-94. doi: 10.1039/c5cp04263a. Epub 2015 Oct 23. PubMed PMID: 26495442. 5: Szkudlarek A, Maciążek-Jurczyk M, Chudzik M, Równicka-Zubik J, Sułkowska A. Alteration of human serum albumin tertiary structure induced by glycation. Spectroscopic study. Spectrochim Acta A Mol Biomol Spectrosc. 2016 Jan 15;153:560-5. doi: 10.1016/j.saa.2015.09.018. Epub 2015 Sep 28. PubMed PMID: 26433342. 6: Ruiz A, Gutiérrez L, Cáceres-Vélez PR, Santos D, Chaves SB, Fascineli ML, Garcia MP, Azevedo RB, Morales MP. Biotransformation of magnetic nanoparticles as a function of coating in a rat model. Nanoscale. 2015 Oct 21;7(39):16321-9. doi: 10.1039/c5nr03780h. PubMed PMID: 26381991. 7: Heinisch T, Pellizzoni M, Dürrenberger M, Tinberg CE, Köhler V, Klehr J, Häussinger D, Baker D, Ward TR. Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design. J Am Chem Soc. 2015 Aug 19;137(32):10414-9. doi: 10.1021/jacs.5b06622. Epub 2015 Aug 7. PubMed PMID: 26226626. 8: Kumar A, Kim HS. N-(3-Imidazolyl)propyl dansylamide as a selective Hg(2+) sensor in aqueous media through electron transfer. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Sep 5;148:250-4. doi: 10.1016/j.saa.2015.03.091. Epub 2015 Mar 28. PubMed PMID: 25897719. 9: Bhoi AK, Das SK, Majhi D, Sahu PK, Nijamudheen A, N A, Rahaman A, Sarkar M. Analyte interactions with a new ditopic dansylamide-nitrobenzoxadiazole dyad: a combined photophysical, NMR, and theoretical (DFT) study. J Phys Chem B. 2014 Aug 21;118(33):9926-37. doi: 10.1021/jp504631n. Epub 2014 Aug 12. PubMed PMID: 25116958. 10: Wagner-Rousset E, Janin-Bussat MC, Colas O, Excoffier M, Ayoub D, Haeuw JF, Rilatt I, Perez M, Corvaïa N, Beck A. 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PubMed PMID: 23079613. 14: zhang Y, Yang X, Liu L, Huang X, Pu J, Long G, Zhang L, Liu D, Xu B, Liao J, Liao F. Comparison of Förster-resonance-energy-transfer acceptors for tryptophan and tyrosine residues in native proteins as donors. J Fluoresc. 2013 Jan;23(1):147-57. doi: 10.1007/s10895-012-1128-z. Epub 2012 Sep 22. Erratum in: J Fluoresc. 2013 Jan;23(1):159. Huang, Zuexia [corrected to Huang, Xuexia]. PubMed PMID: 23001429. 15: Joubert J, van Dyk S, Green IR, Malan SF. Synthesis, evaluation and application of polycyclic fluorescent analogues as N-methyl-D-aspartate receptor and voltage gated calcium channel ligands. Eur J Med Chem. 2011 Oct;46(10):5010-20. doi: 10.1016/j.ejmech.2011.08.008. Epub 2011 Aug 11. PubMed PMID: 21868136. 16: Wu X, Liu J, Wang Q, Xue W, Yao X, Zhang Y, Jin J. Spectroscopic and molecular modeling evidence of clozapine binding to human serum albumin at subdomain IIA. 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