DPQ | CAS#60547-97-9 | antiviral agent

MedKoo Cat#: 561815 | Name: DPQ

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DPQ is an antiviral agent that acts against the H1N1 and H3N2 strains of influenza A as well as influenza B. It has also been shown to bind to a widened RNA major groove at the internal loop.

Chemical Structure

DPQ

CAS#60547-97-9

Theoretical Analysis

MedKoo Cat#: 561815

Name: DPQ

CAS#: 60547-97-9

Chemical Formula: C14H19N5O2

Exact Mass: 289.1539

Molecular Weight: 289.33

Elemental Analysis: C, 58.12; H, 6.62; N, 24.21; O, 11.06

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

DPQ; 2-PADQZ; 2 PADQZ; 2PADQZ;

IUPAC/Chemical Name

6,7-Dimethoxy-2-piperazin-1-ylquinazolin-4-amine

InChi Key

APKHJGDGWQDBGM-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H19N5O2/c1-20-11-7-9-10(8-12(11)21-2)17-14(18-13(9)15)19-5-3-16-4-6-19/h7-8,16H,3-6H2,1-2H3,(H2,15,17,18)

SMILES Code

NC1=C2C=C(OC)C(OC)=CC2=NC(N3CCNCC3)=N1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 289.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Zhou G, Wang L, Ma Y, Wang L, Zhang Y, Jiang W. Synthesis of a quinazoline derivative: a new α₁-adrenoceptor ligand for conjugation to quantum dots to study α₁-adrenoceptors in living cells. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5905-9. doi: 10.1016/j.bmcl.2011.07.122. Epub 2011 Aug 10. PubMed PMID: 21875797. 2: Piotrovskiĭ VK, Veĭko NN, Golovanova IV, Gus'kova TA, Polievktov MK. [Slow elimination of a prazosin metabolite compared to prazosin kinetics after its intravenous administration to rabbits]. Biull Eksp Biol Med. 1987 Jan;103(1):73-5. Russian. PubMed PMID: 3801655. 3: Piotrovskii VK, Veiko NN, Ryabokon OS, Postolnikov SF, Metelitsa VI. Identification of a prazosin metabolite and some preliminary data on its kinetics in hypertensive patients. Eur J Clin Pharmacol. 1984;27(3):275-80. PubMed PMID: 6510454. 4: Althuis TH, Hess HJ. Synthesis and identification of the major metabolites of prazosin formed in dog and rat. J Med Chem. 1977 Jan;20(1):146-9. PubMed PMID: 833813.