MedKoo Cat#: 527493 | Name: AZD3264
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AZD3264 is a novel Inhibitor of IkB-kinase IKK2.

Chemical Structure

AZD3264
AZD3264
CAS#1609281-86-8

Theoretical Analysis

MedKoo Cat#: 527493

Name: AZD3264

CAS#: 1609281-86-8

Chemical Formula: C21H23N5O4S

Exact Mass: 441.1471

Molecular Weight: 441.51

Elemental Analysis: C, 57.13; H, 5.25; N, 15.86; O, 14.49; S, 7.26

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 600.00 2 Weeks
25mg USD 1,050.00 2 Weeks
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Related CAS #
No Data
Synonym
AZD 3264; AZD-3264; AZD3264
IUPAC/Chemical Name
2-(Carbamoylamino)-5-[4-(3,5-dimethyl-1,2-oxazol-4-yl)-2-[(3S)-pyrrolidin-3-yloxy]phenyl]thiophene-3-carboxamide
InChi Key
NMFIXEFNQPDISY-ZDUSSCGKSA-N
InChi Code
InChI=1S/C21H23N5O4S/c1-10-18(11(2)30-26-10)12-3-4-14(16(7-12)29-13-5-6-24-9-13)17-8-15(19(22)27)20(31-17)25-21(23)28/h3-4,7-8,13,24H,5-6,9H2,1-2H3,(H2,22,27)(H3,23,25,28)/t13-/m0/s1
SMILES Code
O=C(C1=C(NC(N)=O)SC(C2=CC=C(C3=C(C)ON=C3C)C=C2O[C@@H]4CNCC4)=C1)N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 441.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Murugan, A., Bachu, S., Manjunatha, S.G., et al. Exploiting the differential reactivities of halogen atoms: Development of a scalable route to IKK2 inhibitor AZD3264 Org. Process Res. Dev. 18(5), 646-651 (2014).