Synonym
Dagadip; Lethox; Endyl; NSC 231691; NSC-231691; NSC231691; CARBOPHENOTHION; Carbofenotion; Trithion Oleoakarithion
IUPAC/Chemical Name
Phosphorodithioic acid, S-(((4-chlorophenyl)thio)methyl) O,O-diethyl ester
InChi Key
VEDTXTNSFWUXGQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H16ClO2PS3/c1-3-13-15(16,14-4-2)18-9-17-11-7-5-10(12)6-8-11/h5-8H,3-4,9H2,1-2H3
SMILES Code
S=P(OCC)(SCSC1=CC=C(Cl)C=C1)OCC
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
342.85
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Clark JR, Patrick JM Jr, Middaugh DP, Moore JC. Relative sensitivity of six estuarine fishes to carbophenothion, chlorpyrifos, and fenvalerate. Ecotoxicol Environ Saf. 1985 Dec;10(3):382-90. PubMed PMID: 2419075.
2: McCarty RT, Haufler M, McBeth CA Jr. Acute toxicity of carbophenothion and demeton in sheep. Am J Vet Res. 1967 Mar;28(123):507-10. PubMed PMID: 6033698.
3: Sánchez-Fortún S, Barahona V. The use of carbamates, atropine, and 2-pyridine aldoxime methoiodide in the protection of Artemia salina against poisoning by carbophenothion. Environ Toxicol Chem. 2001 Sep;20(9):2008-13. PubMed PMID: 11521828.
4: Older JJ, Hatcher RL. Food poisoning caused by carbophenothion. JAMA. 1969 Sep 1;209(9):1328-30. PubMed PMID: 5819901.
5: Stanley PI, Bunyan PJ. Hazards to wintering geese and other wildlife from the use of dieldrin, chlorfenvinphos and carbophenothion as wheat seed treatments. Proc R Soc Lond B Biol Sci. 1979 Jul 18;205(1158):31-45. PubMed PMID: 40240.
6: Uilenberg G, Gaulier R. [Accidental poisoning of cattle by spraying with an organophosphoric insecticide, carbophenothion]. Rev Elev Med Vet Pays Trop. 1965;18(2):175-81. French. PubMed PMID: 5889951.
7: Treeby PJ. Carbophenothion as a sheep dip for the control of blowfly, lice and keds. Vet Rec. 1967 Sep 30;81(14):332-5. PubMed PMID: 6069237.
8: Westlake GE, Bunyan PJ, Stanley PI. Variation in the response of plasma enzyme activities in avian species dosed with carbophenothion. Ecotoxicol Environ Saf. 1978 Sep;2(2):151-9. PubMed PMID: 729517.
9: Brown PM, Uppal GS. Improved clean-up procedure for the determination of small residues of carbophenothion in mice. J Chromatogr. 1980 Mar 21;190(1):201-2. PubMed PMID: 7380946.
10: Nigg HN, Allen JC, King RW, Thompson NP, Edeards GJ, Brooks RF. Dislodgeable residues of parathion and carbophenothion in Florida citrus: a weather model. Bull Environ Contam Toxicol. 1978 May;19(5):578-88. PubMed PMID: 667388.
11: Treeby PJ. Control of an outbreak of gamma-BHC-resistant sheep body lice in the north of England with the phosphoric ester carbophenothion. Vet Rec. 1966 Sep 17;79(12):326-8. PubMed PMID: 6008204.
12: Liu H, Kong W, Gong B, Miao Q, Qi Y, Yang M. Rapid analysis of multi-pesticides in Morinda officinalis by GC-ECD with accelerated solvent extraction assisted matrix solid phase dispersion and positive confirmation by GC-MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Jan 1;974:65-74. doi: 10.1016/j.jchromb.2014.10.017. Epub 2014 Oct 22. PubMed PMID: 25463199.
13: DeBaun JR, Menn JJ. Sulfoxide reduction in relation to organophosphorus insecticide detoxification. Science. 1976 Jan 16;191(4223):187-8. PubMed PMID: 1246606.
14: Baker JA, Jordaan JO, Robertson WD. Ixodicidal resistance in Boophilus microplus (Canestrini) in the Republic of South Africa and Transkei. J S Afr Vet Assoc. 1979 Dec;50(4):296-301. PubMed PMID: 553968.
15: Li X, Gan P, Peng R, Huang C, Yu H. Determination of 23 organophosphorous pesticides in surface water using SPME followed by GC-MS. J Chromatogr Sci. 2010 Mar;48(3):183-7. PubMed PMID: 20223083.
16: Torres CM, Picó Y, Marín R, Mañes J. Evaluation of organophosphorus pesticide residues in citrus fruits from the Valencian community (Spain). J AOAC Int. 1997 Sep-Oct;80(5):1122-8. PubMed PMID: 9325585.
17: Goodspeed DP, Chestnut LI. Determining organohalides in animal fats using gel permeation chromatographic cleanup: repeatability study. J Assoc Off Anal Chem. 1991 Mar-Apr;74(2):388-94. PubMed PMID: 2050618.
18: Thompson NP. Disappearance of dislodgable residues of five organophosphate pesticides on citrus leaves and fruit during dry and wet weather in Florida. Arch Environ Contam Toxicol. 1976;5(1):55-61. PubMed PMID: 1015863.
19: Gutiérrez Valencia TM, García de Llasera MP. Determination of organophosphorus pesticides in bovine tissue by an on-line coupled matrix solid-phase dispersion-solid phase extraction-high performance liquid chromatography with diode array detection method. J Chromatogr A. 2011 Sep 28;1218(39):6869-77. doi: 10.1016/j.chroma.2011.08.011. Epub 2011 Aug 12. PubMed PMID: 21872255.
20: Torres CM, Picó Y, Redondo MJ, Mañes J. Matrix solid-phase dispersion extraction procedure for multiresidue pesticide analysis in oranges. J Chromatogr A. 1996 Jan 5;719(1):95-103. PubMed PMID: 8589838.
