MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 561747 | Name: SDM-25N HCl
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SDM-25N HCl is a selective δ-opioid receptor antagonist.

Chemical Structure

SDM-25N HCl
SDM-25N HCl
CAS#342884-71-3

Theoretical Analysis

MedKoo Cat#: 561747

Name: SDM-25N HCl

CAS#: 342884-71-3

Chemical Formula: C26H27ClN2O3

Exact Mass: 0.0000

Molecular Weight: 450.96

Elemental Analysis: C, 69.25; H, 6.04; Cl, 7.86; N, 6.21; O, 10.64

Price and Availability

Size Price Availability Quantity
10mg USD 310.00
50mg USD 870.00
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
SDM-25N HCl; SDM-25N Hydrochloride; SDM 25N HCl; SDM25N HCl; SDM 25N Hydrochloride; SDM25N Hydrochloride;
IUPAC/Chemical Name
(4bS,8R,8aS,14bR)-5,6,7,8,14,14b-Hexahydro-7-(2-methyl-2-propenyl)-4,8-methanobenzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol hydrochloride
InChi Key
QLLCUVACGPLGAX-IDRHMUJXSA-N
InChi Code
InChI=1S/C26H26N2O3.ClH/c1-14(2)13-28-10-9-25-21-15-7-8-19(29)23(21)31-24(25)22-17(12-26(25,30)20(28)11-15)16-5-3-4-6-18(16)27-22;/h3-8,20,24,27,29-30H,1,9-13H2,2H3;1H/t20-,24+,25+,26-;/m1./s1
SMILES Code
OC1=C(O2)C([C@@]34[C@]2([H])C(NC5=C6C=CC=C5)=C6C[C@@]3(O)[C@]7([H])N(CC(C)=C)CC4)=C(C7)C=C1.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 450.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: van Cleef KW, Overheul GJ, Thomassen MC, Marjakangas JM, van Rij RP. Escape Mutations in NS4B Render Dengue Virus Insensitive to the Antiviral Activity of the Paracetamol Metabolite AM404. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2554-7. doi: 10.1128/AAC.02462-15. Print 2016 Apr. PubMed PMID: 26856827; PubMed Central PMCID: PMC4808173. 2: Ong EW, Xue L, Olmstead MC, Cahill CM. Prolonged morphine treatment alters δ opioid receptor post-internalization trafficking. Br J Pharmacol. 2015 Jan;172(2):615-29. doi: 10.1111/bph.12761. Epub 2014 Jul 1. PubMed PMID: 24819092; PubMed Central PMCID: PMC4292973. 3: van Cleef KW, Overheul GJ, Thomassen MC, Kaptein SJ, Davidson AD, Jacobs M, Neyts J, van Kuppeveld FJ, van Rij RP. Identification of a new dengue virus inhibitor that targets the viral NS4B protein and restricts genomic RNA replication. Antiviral Res. 2013 Aug;99(2):165-71. doi: 10.1016/j.antiviral.2013.05.011. Epub 2013 Jun 2. PubMed PMID: 23735301. 4: Blomeley CP, Bracci E. Opioidergic interactions between striatal projection neurons. J Neurosci. 2011 Sep 21;31(38):13346-56. doi: 10.1523/JNEUROSCI.1775-11.2011. PubMed PMID: 21940429; PubMed Central PMCID: PMC3781771.