MedKoo Cat#: 561731 | Name: PDE9-IN-(S)-C33
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

PDE9-IN-(S)-C33 is a potent and selective inhibitor of phosphodiesterase-9 (PDE9).

Chemical Structure

PDE9-IN-(S)-C33
PDE9-IN-(S)-C33
CAS#2066488-39-7

Theoretical Analysis

MedKoo Cat#: 561731

Name: PDE9-IN-(S)-C33

CAS#: 2066488-39-7

Chemical Formula: C18H20ClN5O

Exact Mass: 357.1356

Molecular Weight: 357.84

Elemental Analysis: C, 60.42; H, 5.63; Cl, 9.91; N, 19.57; O, 4.47

Price and Availability

Size Price Availability Quantity
50mg USD 650.00 2 Weeks
100mg USD 1,150.00 2 Weeks
200mg USD 1,950.00 2 Weeks
500mg USD 2,950.00 2 Weeks
1g USD 4,250.00 2 Weeks
2g USD 6,850.00 2 Weeks
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Synonym
PDE9-IN-(S)-C33; PDE9IN(S)C33; PDE9 IN (S) C33; (S)-C33;
IUPAC/Chemical Name
6-[[(1S)-1-(4-Chlorophenyl)ethyl]amino]-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
InChi Key
FIUCLBJMUGCQTF-NSHDSACASA-N
InChi Code
InChI=1S/C18H20ClN5O/c1-11(12-6-8-13(19)9-7-12)21-18-22-16-15(17(25)23-18)10-20-24(16)14-4-2-3-5-14/h6-11,14H,2-5H2,1H3,(H2,21,22,23,25)/t11-/m0/s1
SMILES Code
O=C1C2=C(N(C3CCCC3)N=C2)N=C(N[C@H](C4=CC=C(Cl)C=C4)C)N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 357.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Huang M, Shao Y, Hou J, Cui W, Liang B, Huang Y, Li Z, Wu Y, Zhu X, Liu P, Wan Y, Ke H, Luo HB. Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol Pharmacol. 2015 Nov;88(5):836-45. doi: 10.1124/mol.115.099747. Epub 2015 Aug 27. PubMed PMID: 26316540; PubMed Central PMCID: PMC4613944.