MedKoo Cat#: 561729 | Name: CP-312
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP-312 is an activator of the antioxidant defense response. It acts by inducing heme oxygenase-1 and protecting human iPSC-derived cardiomyocytes from oxidative stress.

Chemical Structure

CP-312
CP-312
CAS#895470-67-4

Theoretical Analysis

MedKoo Cat#: 561729

Name: CP-312

CAS#: 895470-67-4

Chemical Formula: C16H12ClN3OS2

Exact Mass: 361.0110

Molecular Weight: 361.86

Elemental Analysis: C, 53.11; H, 3.34; Cl, 9.80; N, 11.61; O, 4.42; S, 17.72

Price and Availability

Size Price Availability Quantity
50mg USD 550.00 2 Weeks
100mg USD 950.00 2 Weeks
200mg USD 1,650.00 2 Weeks
500mg USD 2,950.00 2 Weeks
1g USD 4,350.00 2 Weeks
2g USD 6,550.00 2 Weeks
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Related CAS #
No Data
Synonym
CP-312; CP 312; CP312; Cardioprotectant 312;
IUPAC/Chemical Name
2-((4-Chlorophenyl)thio)-N-(4-(pyridin-2-yl)thiazol-2-yl)acetamide
InChi Key
KAWIOCMUARENDQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H12ClN3OS2/c17-11-4-6-12(7-5-11)22-10-15(21)20-16-19-14(9-23-16)13-3-1-2-8-18-13/h1-9H,10H2,(H,19,20,21)
SMILES Code
O=C(NC1=NC(C2=NC=CC=C2)=CS1)CSC3=CC=C(Cl)C=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 361.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kirby RJ, Divlianska DB, Whig K, Bryan N, Morfa CJ, Koo A, Nguyen KH, Maloney P, Peddibhotla S, Sessions EH, Hershberger PM, Smith LH, Malany S. Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress. J Pharmacol Exp Ther. 2018 Jan;364(1):87-96. doi: 10.1124/jpet.117.243717. Epub 2017 Nov 3. PubMed PMID: 29101218.