MedKoo Cat#: 571426 | Name: Capoamycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Capoamycin is an insotatracine antibiotic. It has been investigated for anti tumor properties.

Chemical Structure

Capoamycin
Capoamycin
CAS#97937-29-6

Theoretical Analysis

MedKoo Cat#: 571426

Name: Capoamycin

CAS#: 97937-29-6

Chemical Formula: C35H38O10

Exact Mass: 618.2465

Molecular Weight: 618.68

Elemental Analysis: C, 67.95; H, 6.19; O, 25.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Capoamycin; AC 54; AC54; AC-54
IUPAC/Chemical Name
(2S,3S,4S,6R)-4-hydroxy-2-methyl-6-((4aR,12bR)-4a,8,12b-trihydroxy-3-methyl-1,7,12-trioxo-1,4,4a,7,12,12b-hexahydrotetraphen-9-yl)tetrahydro-2H-pyran-3-yl (2E,4E)-deca-2,4-dienoate
InChi Key
MCNOFFKXBMHLAD-AVBRQSIPSA-N
InChi Code
InChI=1S/C35H38O10/c1-4-5-6-7-8-9-10-11-27(38)45-33-20(3)44-25(17-24(33)36)21-12-13-22-28(30(21)39)31(40)23-14-15-34(42)18-19(2)16-26(37)35(34,43)29(23)32(22)41/h8-16,20,24-25,33,36,39,42-43H,4-7,17-18H2,1-3H3/b9-8+,11-10+/t20-,24-,25+,33+,34-,35+/m0/s1
SMILES Code
CCCCC/C=C/C=C/C(O[C@@H]1[C@H](C)O[C@@H](C2=CC=C(C(C3=O)=C2O)C(C4=C3C=C[C@@]5(O)[C@@]4(O)C(C=C(C)C5)=O)=O)C[C@@H]1O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 618.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hayakawa Y, Iwakiri T, Imamura K, Seto H, Otake N. Studies on the isotetracenone antibiotics. I. Capoamycin, a new antitumor antibiotic. J Antibiot (Tokyo). 1985 Jul;38(7):957-9. PubMed PMID: 3839783. 2: Sawa R, Matsuda N, Uchida T, Ikeda T, Sawa T, Naganawa H, Hamada M, Takeuchi T. Dioxamycin, a new benz[a]anthraquinone antibiotic. J Antibiot (Tokyo). 1991 Apr;44(4):396-402. PubMed PMID: 2032948. 3: Xin W, Ye X, Yu S, Lian XY, Zhang Z. New capoamycin-type antibiotics and polyene acids from marine Streptomyces fradiae PTZ0025. Mar Drugs. 2012 Oct 29;10(11):2388-402. doi: 10.3390/md10112388. PubMed PMID: 23203266; PubMed Central PMCID: PMC3509524. 4: Osda H. [Differentiation inducing compounds]. Tanpakushitsu Kakusan Koso. 1993 Aug;38(11):1791-9. Review. Japanese. PubMed PMID: 8210426.