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MedKoo Cat#: 527014 | Name: Methoxyfenozide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Methoxyfenozide is an insect growth regulator used in the control lepidopteran insect pests.

Chemical Structure

Methoxyfenozide
Methoxyfenozide
CAS#161050-58-4

Theoretical Analysis

MedKoo Cat#: 527014

Name: Methoxyfenozide

CAS#: 161050-58-4

Chemical Formula: C22H28N2O3

Exact Mass: 368.2100

Molecular Weight: 368.48

Elemental Analysis: C, 71.71; H, 7.66; N, 7.60; O, 13.03

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Methoxyfenozide
IUPAC/Chemical Name
N'-(tert-Butyl )-N'-(3,5-dimethylbenzoyl)-3-methoxy-2-methylbenzohydrazide
InChi Key
QCAWEPFNJXQPAN-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H28N2O3/c1-14-11-15(2)13-17(12-14)21(26)24(22(4,5)6)23-20(25)18-9-8-10-19(27-7)16(18)3/h8-13H,1-7H3,(H,23,25)
SMILES Code
O=C(NN(C(C)(C)C)C(C1=CC(C)=CC(C)=C1)=O)C2=CC=CC(OC)=C2C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 368.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bosch D, Rodríguez MA, Avilla J. Monitoring resistance of Cydia pomonella (L.) Spanish field populations to new chemical insecticides and the mechanisms involved. Pest Manag Sci. 2017 Nov 16. doi: 10.1002/ps.4791. [Epub ahead of print] PubMed PMID: 29148167. 2: Shuijin H, Qiong C, Wenjing Q, Yang S, Houguo Q. Resistance Monitoring of Four Insecticides and a Description of an Artificial Diet Incorporation Method for Chilo suppressalis (Lepidoptera: Crambidae). J Econ Entomol. 2017 Dec 5;110(6):2554-2561. doi: 10.1093/jee/tox266. PubMed PMID: 29045662. 3: Silva RS, Arcanjo LP, Soares JRS, Ferreira DO, Serrão JE, Martins JC, Costa ÁH, Picanço MC. Insecticide toxicity to the borer Neoleucinodes elegantalis (Guenée) (Lepidoptera: Crambidae): developmental and egg-laying effects. Neotrop Entomol. 2017 Aug 18. doi: 10.1007/s13744-017-0553-8. [Epub ahead of print] PubMed PMID: 28822099. 4: Ling J, Li R, Nwafor CC, Cheng J, Li M, Xu Q, Wu J, Gan L, Yang Q, Liu C, Chen M, Zhou Y, Cahoon EB, Zhang C. Development of iFOX-hunting as a functional genomic tool and demonstration of its use to identify early senescence-related genes in the polyploid Brassica napus. Plant Biotechnol J. 2017 Jul 17. doi: 10.1111/pbi.12799. [Epub ahead of print] PubMed PMID: 28718508. 5: Berset JD, Mermer S, Robel AE, Walton VM, Chien ML, Field JA. Direct residue analysis of systemic insecticides and some of their relevant metabolites in wines by liquid chromatography - mass spectrometry. J Chromatogr A. 2017 Jul 14;1506:45-54. doi: 10.1016/j.chroma.2017.05.019. Epub 2017 May 13. PubMed PMID: 28549715. 6: Brikis CJ, Zarei A, Trobacher CP, DeEll JR, Akama K, Mullen RT, Bozzo GG, Shelp BJ. Ancient Plant Glyoxylate/Succinic Semialdehyde Reductases: GLYR1s Are Cytosolic, Whereas GLYR2s Are Localized to Both Mitochondria and Plastids. Front Plant Sci. 2017 Apr 21;8:601. doi: 10.3389/fpls.2017.00601. eCollection 2017. PubMed PMID: 28484477; PubMed Central PMCID: PMC5399074. 7: Chai Y, Gao G, Shen S, Liu X, Lu C. Neutral losses of sodium benzoate and benzoic acid in the fragmentation of the [M + Na](+) ions of methoxyfenozide and tebufenozide via intramolecular rearrangement in electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom. 2017 Feb 15;31(3):245-252. doi: 10.1002/rcm.7785. PubMed PMID: 28110498. 8: Childs LM, Cai FY, Kakani EG, Mitchell SN, Paton D, Gabrieli P, Buckee CO, Catteruccia F. Disrupting Mosquito Reproduction and Parasite Development for Malaria Control. PLoS Pathog. 2016 Dec 15;12(12):e1006060. doi: 10.1371/journal.ppat.1006060. eCollection 2016 Dec. PubMed PMID: 27977810; PubMed Central PMCID: PMC5158081. 9: Siddiqui AA, Khaki PS, Bano B. Interaction of almond cystatin with pesticides: Structural and functional analysis. J Mol Recognit. 2017 Mar;30(3). doi: 10.1002/jmr.2586. Epub 2016 Oct 27. PubMed PMID: 27785842. 10: Ono ÉK, Zanardi OZ, Aguiar Santos KF, Yamamoto PT. Susceptibility of Ceraeochrysa cubana larvae and adults to six insect growth-regulator insecticides. Chemosphere. 2017 Feb;168:49-57. doi: 10.1016/j.chemosphere.2016.10.061. Epub 2016 Oct 22. PubMed PMID: 27776238. 11: Khan HAA, Akram W. Cyromazine resistance in a field strain of house flies, Musca domestica L.: Resistance risk assessment and bio-chemical mechanism. Chemosphere. 2017 Jan;167:308-313. doi: 10.1016/j.chemosphere.2016.10.018. Epub 2016 Oct 11. PubMed PMID: 27728890. 12: Shah RM, Alam M, Ahmad D, Waqas M, Ali Q, Binyamin M, Shad SA. Toxicity of 25 synthetic insecticides to the field population of Culex quinquefasciatus Say. Parasitol Res. 2016 Nov;115(11):4345-4351. Epub 2016 Aug 17. PubMed PMID: 27530515. 13: Mason KS, Roubos CR, Teixeira LA, Isaacs R. Spatially Targeted Applications of Reduced-Risk Insecticides for Economical Control of Grape Berry Moth, Paralobesia viteana (Lepidoptera: Tortricidae). J Econ Entomol. 2016 Jul 19. pii: tow158. [Epub ahead of print] PubMed PMID: 27435929. 14: LaLone CA, Villeneuve DL, Lyons D, Helgen HW, Robinson SL, Swintek JA, Saari TW, Ankley GT. Editor's Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity. Toxicol Sci. 2016 Oct;153(2):228-45. doi: 10.1093/toxsci/kfw119. Epub 2016 Jun 30. PubMed PMID: 27370413. 15: Wing KD. It takes a team: reflections on insecticide discoveries, toxicological problems and enjoying the unexpected. Pest Manag Sci. 2017 Apr;73(4):666-671. doi: 10.1002/ps.4311. Epub 2016 Jun 6. PubMed PMID: 27146911. 16: Rugno GR, Zanardi OZ, Bajonero Cuervo J, de Morais MR, Yamamoto PT. Impact of insect growth regulators on the predator Ceraeochrysa cincta (Schneider) (Neuroptera: Chrysopidae). Ecotoxicology. 2016 Jul;25(5):940-9. doi: 10.1007/s10646-016-1651-9. Epub 2016 Apr 30. PubMed PMID: 27137778. 17: Shah RM, Shad SA, Abbas N. Methoxyfenozide resistance of the housefly, Musca domestica L. (Diptera: Muscidae): cross-resistance patterns, stability and associated fitness costs. Pest Manag Sci. 2017 Jan;73(1):254-261. doi: 10.1002/ps.4296. Epub 2016 May 25. PubMed PMID: 27098995. 18: Rodriguez-Saona C, Wanumen AC, Salamanca J, Holdcraft R, Kyryczenko-Roth V. Toxicity of Insecticides on Various Life Stages of Two Tortricid Pests of Cranberries and on a Non-Target Predator. Insects. 2016 Apr 15;7(2). pii: E15. doi: 10.3390/insects7020015. PubMed PMID: 27092527; PubMed Central PMCID: PMC4931427. 19: Miyata K, Nakagawa Y, Kimura Y, Ueda K, Akamatsu M. In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines. Toxicol Appl Pharmacol. 2016 May 1;298:40-7. doi: 10.1016/j.taap.2016.03.008. Epub 2016 Mar 17. PubMed PMID: 26995013. 20: Khan HA, Akram W, Arshad M, Hafeez F. Toxicity and resistance of field collected Musca domestica (Diptera: Muscidae) against insect growth regulator insecticides. Parasitol Res. 2016 Apr;115(4):1385-90. doi: 10.1007/s00436-015-4872-6. Epub 2015 Dec 28. PubMed PMID: 26711449.