Synonym
Thionazin; Zynophos; AC 18133; AC-18133; AC18133
IUPAC/Chemical Name
O,O-Diethyl O-pyrazin-2-yl phosphorothioate
InChi Key
IRVDMKJLOCGUBJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H13N2O3PS/c1-3-11-14(15,12-4-2)13-8-7-9-5-6-10-8/h5-7H,3-4H2,1-2H3
SMILES Code
S=P(OCC)(OCC)OC1=NC=CN=C1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
248.24
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Salemi A, Rasoolzadeh R, Nejad MM, Vosough M. Ultrasonic assisted headspace single drop micro-extraction and gas chromatography with nitrogen-phosphorus detector for determination of organophosphorus pesticides in soil. Anal Chim Acta. 2013 Mar 26;769:121-6. doi: 10.1016/j.aca.2013.01.054. Epub 2013 Feb 8. PubMed PMID: 23498130.
2: Basheer C, Alnedhary AA, Rao BS, Lee HK. Determination of organophosphorous pesticides in wastewater samples using binary-solvent liquid-phase microextraction and solid-phase microextraction: a comparative study. Anal Chim Acta. 2007 Dec 19;605(2):147-52. Epub 2007 Oct 11. PubMed PMID: 18036377.
3: Kochman M, Gordin A, Alon T, Amirav A. Flow modulation comprehensive two-dimensional gas chromatography-mass spectrometry with a supersonic molecular beam. J Chromatogr A. 2006 Sep 29;1129(1):95-104. Epub 2006 Jul 10. PubMed PMID: 16834991.
4: Basheer C, Balaji G, Chua SH, Valiyaveettil S, Lee HK. Novel on-site sample preparation approach with a portable agitator using functional polymer-coated multi-fibers for the microextraction of organophosphorus pesticides in seawater. J Chromatogr A. 2011 Feb 4;1218(5):654-61. doi: 10.1016/j.chroma.2010.12.033. Epub 2010 Dec 16. PubMed PMID: 21208618.
5: Fiori G, Saglini V, Bertini F, Domenighetti G, Mombelli G. [Severe poisoning with the organophosphorus insecticide thionazine--2 cases with the development of adult respiratory distress syndrome (ARDS)]. Schweiz Med Wochenschr. 1987 Mar 14;117(11):399-401. French. PubMed PMID: 3576150.
6: Sepulcri F, Angehrn W, Wolf C. [Severe poisoning with a cholinesterase inhibitor]. Schweiz Med Wochenschr. 1987 Mar 28;117(13):487-90. German. PubMed PMID: 3576159.
7: Skrbić B. Organochlorine and organophosphate pesticide residues in wheat varieties from Serbia. Food Addit Contam. 2007 Jul;24(7):695-703. PubMed PMID: 17613054.
