MedKoo Cat#: 561663 | Name: CP-380736
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

Chemical Structure

CP-380736
CP-380736
CAS#179688-29-0

Theoretical Analysis

MedKoo Cat#: 561663

Name: CP-380736

CAS#: 179688-29-0

Chemical Formula: C14H18N2O5

Exact Mass: 294.1216

Molecular Weight: 294.30

Elemental Analysis: C, 57.14; H, 6.16; N, 9.52; O, 27.18

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
10g USD 400.00 2 Weeks
25g USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
CP-380736; CP 380736; CP380736; PF-00520893; PF 00520893; PF00520893;
IUPAC/Chemical Name
6,7-Bis(2-methoxyethoxy)-1H-quinazolin-4-one
InChi Key
PMQWTUWLIGJTQD-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
SMILES Code
O=C1N=CNC2=C1C=C(OCCOC)C(OCCOC)=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 294.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL