MedKoo Cat#: 526490 | Name: SKF1
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SKF1 is a suppressor of the ability of FK506 to inhibit cell growth in the presence of high levels of NaCl, inducing cell death in low salt conditions, interacting directly with yeast mitochodria.

Chemical Structure

SKF1
SKF1
CAS#678997-25-6

Theoretical Analysis

MedKoo Cat#: 526490

Name: SKF1

CAS#: 678997-25-6

Chemical Formula: C23H37ClN2O2

Exact Mass: 408.2500

Molecular Weight: 409.01

Elemental Analysis: C, 67.54; H, 9.12; Cl, 8.67; N, 6.85; O, 7.82

Price and Availability

Size Price Availability Quantity
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
SKF1
IUPAC/Chemical Name
Cyclohexylmethyl 4-[imino(octylamino)methyl]benzoate hydrochloride
InChi Key
URYYYIJUCLTKBY-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H36N2O2.ClH/c1-2-3-4-5-6-10-17-25-22(24)20-13-15-21(16-14-20)23(26)27-18-19-11-8-7-9-12-19;/h13-16,19H,2-12,17-18H2,1H3,(H2,24,25);1H
SMILES Code
O=C(OCC1CCCCC1)C2=CC=C(C(NCCCCCCCC)=N)C=C2.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 409.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Butcher RA, Schreiber SL. A small molecule suppressor of FK506 that targets the mitochondria and modulates ionic balance in Saccharomyces cerevisiae. Chem Biol. 2003 Jun;10(6):521-31. PubMed PMID: 12837385.