MedKoo Cat#: 571379 | Name: Abikoviromycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Abikoviromycin is an antiviral agent.

Chemical Structure

Abikoviromycin
Abikoviromycin
CAS#31774-33-1

Theoretical Analysis

MedKoo Cat#: 571379

Name: Abikoviromycin

CAS#: 31774-33-1

Chemical Formula: C10H11NO

Exact Mass: 161.0841

Molecular Weight: 161.20

Elemental Analysis: C, 74.51; H, 6.88; N, 8.69; O, 9.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
IUPAC/Chemical Name
Cyclopent(b)oxireno(c)pyridine, 7-ethylidene-1a,2,3,7-tetrahydro-, (1aR,7E,7aS)-
InChi Key
KQSFHAWSULOGRI-IQPPKSMTSA-N
InChi Code
InChI=1S/C10H11NO/c1-2-7-3-4-8-10(7)9(12-10)5-6-11-8/h2-4,9H,5-6H2,1H3/b7-2+/t9-,10+/m1/s1
SMILES Code
C/C=C1C=CC2=NCC[C@]3([H])[C@@]2\1O3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 161.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: SAKAGAMI Y, UTAHARA R, YAGISHITA K, UMEZAWA H. Identity of latumcidin with abikoviromycin. J Antibiot (Tokyo). 1958 Sep;11(9):231-2. PubMed PMID: 13610782. 2: Kono Y, Takeuchi S, Yonehara H, Marumo F, Saito Y. The structure of latumcidin (abikoviromycin) determined by x-ray analysis. J Antibiot (Tokyo). 1970 Nov;23(11):572-3. PubMed PMID: 5487134. 3: Maruyama H, Okamoto S, Kubo Y, Tsuji G, Fujii I, Ebizuka Y, Furihata K, Hayakawa Y, Nagasawa H, Sakuda S. Isolation of abikoviromycin and dihydroabikoviromycin as inhibitors of polyketide synthase involved in melanin biosynthesis by Colletotrichum lagenarium. J Antibiot (Tokyo). 2003 Sep;56(9):801-4. PubMed PMID: 14632292. 4: UMEZAWA H, TAZAKI T, FUKUYAMA S. An antiviral substance, abikoviromycin, produced by Streptomyces species. Jpn J Med. 1951 Oct;4(5):331-46. PubMed PMID: 14927269. 5: SAKAGAMI Y, YAMAGUCHI I, YONEHARA H, OKIMOTO Y, YAMANOUCHI S, TAKIGUCHI K, SAKAI H. Latumcidin, a new antibiotic from Streptomyces sp. J Antibiot (Tokyo). 1958 Jan;11(1):6-13. PubMed PMID: 13525247. 6: Gurevich AI, Kolosov MN, Korobko VG, Onoprienko VV. The structure of abikoviromycin. Tetrahedron Lett. 1968 Mar;18:2209-12. PubMed PMID: 5651005. 7: Roĭkhel' VM, Zeĭtlenok NA. [Antiviral effect of abikoviromycin]. Antibiotiki. 1969 Nov;14(11):969-73. Russian. PubMed PMID: 5378167. 8: Tsuruoka T, Shomura T, Ogawa Y, Ezaki N, Watanabe H. Some properties of SF-973 B substance, the enzyme catalyzing the conversion of dihydroabikoviromycin to abikoviromycin. J Antibiot (Tokyo). 1973 Mar;26(3):168-74. PubMed PMID: 4783200.