S(-)-8-Hydroxy-DPAT hydrobromide | CAS#78095-20-2

MedKoo Cat#: 526428 | Name: S(-)-8-Hydroxy-DPAT hydrobromide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

S(-)-8-Hydroxy-DPAT hydrobromide is an artial 5-HT1A serotonin receptor agonist.

Chemical Structure

S(-)-8-Hydroxy-DPAT hydrobromide

CAS#78095-20-2

Theoretical Analysis

MedKoo Cat#: 526428

Name: S(-)-8-Hydroxy-DPAT hydrobromide

CAS#: 78095-20-2

Chemical Formula: C16H26BrNO

Exact Mass: 327.1200

Molecular Weight: 328.29

Elemental Analysis: C, 58.54; H, 7.98; Br, 24.34; N, 4.27; O, 4.87

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

S(-)-8-Hydroxy-DPAT hydrobromide

IUPAC/Chemical Name

(7S)-7-(Dipropylamino)-5,6,7,8-tetrahydro-1-naphthalenol hydrobromide

InChi Key

BATPBOZTBNNDLN-UQKRIMTDSA-N

InChi Code

InChI=1S/C16H25NO.BrH/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14;/h5-7,14,18H,3-4,8-12H2,1-2H3;1H/t14-;/m0./s1

SMILES Code

OC1=C2C[C@@H](N(CCC)CCC)CCC2=CC=C1.[H]Br

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 328.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wierońska JM, Sławińska A, Łasoń-Tyburkiewicz M, Gruca P, Papp M, Zorn SH, Doller D, Kłeczek N, Noworyta-Sokołowska K, Gołembiowska K, Pilc A. The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies. Psychopharmacology (Berl). 2015 Jan;232(1):259-73. doi: 10.1007/s00213-014-3657-4. Epub 2014 Jul 11. PubMed PMID: 25012236; PubMed Central PMCID: PMC4281359. 2: Taffe MA, Davis SA, Yuan J, Schroeder R, Hatzidimitriou G, Parsons LH, Ricaurte GA, Gold LH. Cognitive performance of MDMA-treated rhesus monkeys: sensitivity to serotonergic challenge. Neuropsychopharmacology. 2002 Dec;27(6):993-1005. PubMed PMID: 12464456. 3: Schmitz D, Gloveli T, Empson RM, Draguhn A, Heinemann U. Serotonin reduces synaptic excitation in the superficial medial entorhinal cortex of the rat via a presynaptic mechanism. J Physiol. 1998 Apr 1;508 ( Pt 1):119-29. PubMed PMID: 9490827; PubMed Central PMCID: PMC2230865.