MedKoo Cat#: 561614 | Name: Lomifylline

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lomifylline is an inducer of Ca2+-release from intracellular stores via the ryanodine receptor.

Chemical Structure

Lomifylline
Lomifylline
CAS#10226-54-7

Theoretical Analysis

MedKoo Cat#: 561614

Name: Lomifylline

CAS#: 10226-54-7

Chemical Formula: C13H18N4O3

Exact Mass: 278.1379

Molecular Weight: 278.31

Elemental Analysis: C, 56.10; H, 6.52; N, 20.13; O, 17.25

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Related CAS #
No Data
Synonym
Lomifylline; Cervilane;
IUPAC/Chemical Name
1,3-Dimethyl-7-(5-oxohexyl)-1H-purine-2,6(3H,7H)-dione
InChi Key
XBEDAMVJWVPVDS-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H18N4O3/c1-9(18)6-4-5-7-17-8-14-11-10(17)12(19)16(3)13(20)15(11)2/h8H,4-7H2,1-3H3
SMILES Code
O=C(N1C)N(C)C2=C(N(CCCCC(C)=O)C=N2)C1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Lomifylline is an inducer of Ca2+-release from intracellular stores via the ryanodine receptor.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 278.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Le Poncin-Lafitte M, Grosdemouge C, Billon CR, Duterte D, Pontrat P, Lespinasse P, Rapin JR. Short-term memory and cerebral ischemia: pharmacological application. Eur Neurol. 1981;20(3):265-9. PubMed PMID: 7262126.