B1912 | CAS#24028-59-9 | antibacterial agent

MedKoo Cat#: 584103 | Name: B1912

Description:

WARNING: This product is for research use only, not for human or veterinary use.

B1912 is an antibacterial agent.

Chemical Structure

B1912

CAS#24028-59-9

Theoretical Analysis

MedKoo Cat#: 584103

Name: B1912

CAS#: 24028-59-9

Chemical Formula: C30H29ClN4

Exact Mass: 480.2081

Molecular Weight: 481.04

Elemental Analysis: C, 74.91; H, 6.08; Cl, 7.37; N, 11.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

B1912; B-1912; B 1912.

IUPAC/Chemical Name

8-Chloro-3-(cyclohexylmino)-3,5-dihydro-N,5-diphenyl-2-phenazinamine

InChi Key

HTAJQJZZHQMHBK-UHFFFAOYSA-N

InChi Code

InChI=1S/C30H29ClN4/c31-21-16-17-29-27(18-21)34-28-19-25(32-22-10-4-1-5-11-22)26(33-23-12-6-2-7-13-23)20-30(28)35(29)24-14-8-3-9-15-24/h1,3-5,8-11,14-20,23,26,32-33H,2,6-7,12-13H2

SMILES Code

ClC1=CC2=C(C=C1)N(C3=CC=CC=C3)C4=CC(NC5CCCCC5)C(NC6=CC=CC=C6)=CC4=N2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 481.04 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Moynihan R. Canadian media company demands right to publish direct to consumer drug advertising. BMJ. 2009 May 8;338:b1912. doi: 10.1136/bmj.b1912. PubMed PMID: 19429658. 2: Morrison NE. Abortifacient activity of B1912. Int J Lepr Other Mycobact Dis. 1979 Dec;47(4):613-4. PubMed PMID: 122637. 3: Reich CV, de la Cruz E. The effect on pregnant mice of 0.05% B1912 fed in the diet. Int J Lepr Other Mycobact Dis. 1979 Dec;47(4):612-3. PubMed PMID: 122636. 4: Morrison NE, Marley GM. Comparative DNA binding studies with clofazimine and B1912. Int J Lepr Other Mycobact Dis. 1977 Apr-Jun;45(2):188-9. PubMed PMID: 561764. 5: Holmes IB, Banerjee DK, Hilson GR. Effect of rifampin, clofazimine, and B1912 on the viability of Mycobacterium leprae in established mouse footpad infection. Proc Soc Exp Biol Med. 1976 Apr;151(4):637-41. PubMed PMID: 772686. 6: Banerjee DK, Holmes IB. In vitro and in vivo studies of the action of rifampicin, clofazimine and B1912 on Mycobacterium marinum. Chemotherapy. 1976;22(3-4):242-52. PubMed PMID: 1269290.