1: Opitz K. The effect of clonidine and related substances on voluntary ethanol consumption in rats. Drug Alcohol Depend. 1990 Feb;25(1):43-8. doi: 10.1016/0376-8716(90)90139-6. PMID: 1969792.
2: Kwon YW, Zhong Q, Wei XY, Zheng W, Triggle DJ. The interactions of 1,4-dihydropyridines bearing a 2-(2-aminoethylthio)methyl substituent at voltage-dependent Ca2+ channels of smooth muscle, cardiac muscle and neuronal tissues. Naunyn Schmiedebergs Arch Pharmacol. 1990 Jan-Feb;341(1-2):128-36. doi: 10.1007/BF00195069. PMID: 2156174.
3: Roden DM, Nadeau JH, Primm RK. Electrophysiologic and hemodynamic effects of chronic oral therapy with the alpha 2-agonists clonidine and tiamenidine in hypertensive volunteers. Clin Pharmacol Ther. 1988 Jun;43(6):648-54. doi: 10.1038/clpt.1988.90. PMID: 2897889.
4: Kobinger W. Rudolf Buchheim lecture. Drugs as tools in research on adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol. 1986 Feb;332(2):113-23. doi: 10.1007/BF00511400. PMID: 3010138.
5: Struthers AD, Dollery CT. Central nervous system mechanisms in blood pressure control. Eur J Clin Pharmacol. 1985;28 Suppl:3-11. doi: 10.1007/BF00543703. PMID: 2865146.
6: Hamilton BP, Mersey JH, Hamilton J, Kuzbida G, Pavlis R, Levinson P. Withdrawal phenomena in subjects with essential hypertension on clonidine or tiamenidine. Clin Pharmacol Ther. 1984 Nov;36(5):628-33. doi: 10.1038/clpt.1984.232. PMID: 6488684.
7: Reid JL, Campbell BC, Hamilton CA. Withdrawal reactions following cessation of central alpha-adrenergic receptor agonists. Hypertension. 1984 Sep-Oct;6(5 Pt 2):II71-5. doi: 10.1161/01.hyp.6.5_pt_2.ii71. PMID: 6150002.
8: Roach AG, Doxey JC, Strachan DA, Cavero I. Sleeping times evoked by alpha adrenoceptor agonists in two-day-old chicks: an experimental model to evaluate full and partial agonists at central alpha-2 adrenoceptors. J Pharmacol Exp Ther. 1983 Nov;227(2):421-8. PMID: 6138427.
9: Doxey JC, Frank LW, Hersom AS. Studies on the pre- and postjunctional activities of alpha-adrenoreceptor agonists and their cardiovascular effects in the anaesthetized rat. J Auton Pharmacol. 1981 Mar;1(2):157-69. doi: 10.1111/j.1474-8673.1981.tb00508.x. PMID: 6121811.
10: Eckert HG, Baudner S, Weimer KE, Wissmann H. Determination of tiamenidine in biological specimens by radioimmunoassay. Arzneimittelforschung. 1981;31(3):419-24. PMID: 7194666.
11: Hansson BG, Hökfelt B. Changes in blood pressure, plasma catecholamines and plasma renin activity during and after treatment with tiamenidine and clonidine. Br J Clin Pharmacol. 1981 Jan;11(1):73-7. doi: 10.1111/j.1365-2125.1981.tb01105.x. PMID: 7011348; PMCID: PMC1401688.
12: Summers RJ, Jarrott B, Louis WJ. Selectivity of a series of clonidine-like drugs for alpha 1 and alpha 2 adrenoceptors in rat brain. Neurosci Lett. 1980 Dec;20(3):347-50. doi: 10.1016/0304-3940(80)90172-x. PMID: 6255379.
13: Campbell BC, Elliott HL, Hamilton CA, Reid JL. Changes in blood pressure, heart rate, and sympathetic activity on abrupt withdrawal of tiamenidine (HOE 440) in essential hypertension. Eur J Clin Pharmacol. 1980 Nov;18(6):449-54. doi: 10.1007/BF00874654. PMID: 7461012.
14: Summers RJ, Jarrott B, Louis WJ. Displacement of [3H]clonidine binding by clonidine analogues in membranes from rat cerebral cortex. Eur J Pharmacol. 1980 Aug 29;66(2-3):233-41. doi: 10.1016/0014-2999(80)90147-8. PMID: 6254785.
15: Finch L, Hicks PE. Cardiovascular withdrawal effects of clonidine and tiamenidine on abrupt cessation of oral treatment in conscious cats. J Pharm Pharmacol. 1980 Apr;32(4):272-7. doi: 10.1111/j.2042-7158.1980.tb12911.x. PMID: 6103057.
16: Gerlis LS, Wright N. Abrupt withdrawal of the antihypertensive agent tiamenidine after 12-months' treatment. Pharmatherapeutica. 1980;2(6):408-11. PMID: 7001495.
17: Zamboulis C, Hossmann V, Dollery CT, Eckert H. Tiamenidine, a centrally acting antihypertensive drug in essential hypertension [proceedings]. Br J Clin Pharmacol. 1979 Oct;8(4):390P. PMID: 508528.
18: Doxey JC. Pre- and postsynaptic effects of alpha-agonists in the anococcygeus muscle of the pithed rat. Eur J Pharmacol. 1979 Feb 15;54(1-2):185-9. doi: 10.1016/0014-2999(79)90423-0. PMID: 33816.
19: Zapata AM, García MP, Cabrera AS, García MR. Effects of centrally applied thiamenidine on pressure response to central nervous system stimulation. Cor Vasa. 1979;21(1):71-8. PMID: 477332.
20: Bryce TA, Burrows JL. Quantitative analysis of tiamenidine in human plasma by gas chromatography mass spectrometry of a dibenzyl derivative. Biomed Mass Spectrom. 1979 Jan;6(1):27-30. doi: 10.1002/bms.1200060107. PMID: 427259.