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MedKoo Cat#: 530951 | Name: RH02007

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RH02007, also known as CCG-40788, is an inhibitor of the human papillomavirus (HPV) E6 oncoprotein.

Chemical Structure

RH02007
RH02007
CAS#64191-06-6

Theoretical Analysis

MedKoo Cat#: 530951

Name: RH02007

CAS#: 64191-06-6

Chemical Formula: C17H16N2O4

Exact Mass: 312.1110

Molecular Weight: 312.33

Elemental Analysis: C, 65.38; H, 5.16; N, 8.97; O, 20.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
RH02007; RH-02007; RH 02007; CCG-40788; CCG 40788; CCG40788.
IUPAC/Chemical Name
(2,5-Dioxopyrrolidin-1-yl) 4-(2,5-dimethylpyrrol-1-yl)benzoate
InChi Key
XZFYSTPLSPZNKJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H16N2O4/c1-11-3-4-12(2)18(11)14-7-5-13(6-8-14)17(22)23-19-15(20)9-10-16(19)21/h3-8H,9-10H2,1-2H3
SMILES Code
O=C(ON1C(CCC1=O)=O)C2=CC=C(N3C(C)=CC=C3C)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Cervical cancer is the sixth most common cancer in women worldwide and the leading cause of women’s death in developing countries. Nearly all cervical cancers are associated with infection of the human papillomavirus (HPV).

Preparing Stock Solutions

The following data is based on the product molecular weight 312.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145632/ ACS Chem Biol. 2014 Jul 18; 9(7): 1603–1612. Published online 2014 May 22. doi: 10.1021/cb500229d PMCID: PMC4145632 NIHMSID: NIHMS622498 Identification and Characterization of Small Molecule Human Papillomavirus E6 Inhibitors Kimberly A. Malecka,†‡⊥ Daniela Fera,†‡⊥ David C. Schultz,† Santosh Hodawadekar,† Melvin Reichman,§ Preston S. Donover,§ Maureen E. Murphy,† and Ronen Marmorstein*†‡∥