Synonym
MDK-4111; MDK 4111; MDK4111, GPR120 Agonist 2
IUPAC/Chemical Name
4-[(5-Chloro-2,3-dihydro-2,2-dimethyl-7-benzofuranyl)methoxy]-2,3-dimethylbenzenepropanoic acid
InChi Key
KOHMUAMPZUHGNV-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H25ClO4/c1-13-14(2)19(7-5-15(13)6-8-20(24)25)26-12-17-10-18(23)9-16-11-22(3,4)27-21(16)17/h5,7,9-10H,6,8,11-12H2,1-4H3,(H,24,25)
SMILES Code
O=C(O)CCC1=CC=C(OCC2=C(OC(C)(C)C3)C3=CC(Cl)=C2)C(C)=C1C
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Compound of CAS#1234844-11-1 has no established name yet. We temporally name it as MDK-4111 for the convenience of commmunication.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
388.89
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1. Preparation of benzofuran derivatives as GPR120 receptor agonists
By Shi, Dong Fang; Song, Jiangao; Ma, Jingyuan; Novack, Aaron; Pham, Phuongly; Nashashibi, Imad Fayek; Rabbat, Christopher J.; Chen, Xin
From U.S. Pat. Appl. Publ. (2011), US 20110313003 A1 20111222. | Language: English, Database: CAPLUS
2. Preparation of benzofuran derivatives as GPR120 receptor agonists
By Shi, Dong Fang; Song, Jiangao; Ma, Jingyuan; Novack, Aaron; Pham, Phuongly; Nashashibi, Imad; Rabbat, Christopher J.; Chen, Xin
From PCT Int. Appl. (2011), WO 2011159297 A1 20111222. | Language: English, Database: CAPLUS
3. Preparation of benzofuranyl substituted phenylalkylcarboxylic acids as Gpr120 receptor agonists
By Shi, Dong Fang; Song, Jiangao; Ma, Jingyuan; Novack, Aaron; Pham, Phuongly; Nashashibi, Imad; Rabbat, Christopher J.; Chen, Xin
From PCT Int. Appl. (2010), WO 2010080537 A1 20100715. | Language: English, Database: CAPLUS
