MedKoo Cat#: 530940 | Name: NS-6784

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NS-6784 is discontinued. Customer who is interested in this product may contact DanPET AB (website www.danpet.eu).

Chemical Structure

NS-6784
NS-6784
CAS#677723-97-6

Theoretical Analysis

MedKoo Cat#: 530940

Name: NS-6784

CAS#: 677723-97-6

Chemical Formula: C15H18N4O

Exact Mass: 270.1481

Molecular Weight: 270.34

Elemental Analysis: C, 66.64; H, 6.71; N, 20.73; O, 5.92

Price and Availability

This product was removed for the commercial reasons.
Related CAS #
No Data
Synonym
NS-6784; NS 6784; NS6784.
IUPAC/Chemical Name
4-(5-Phenyl-1,3,4-oxadiazol-2-yl)-1,4-diazabicyclo[3.2.2]nonane
InChi Key
NFQNAHNFWFCCMJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H18N4O/c1-2-4-12(5-3-1)14-16-17-15(20-14)19-11-10-18-8-6-13(19)7-9-18/h1-5,13H,6-11H2
SMILES Code
N1(CC2)CCN(C3=NN=C(C4=CC=CC=C4)O3)C2CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 270.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ween H, Thorin-Hagene K, Andersen E, Grønlien JH, Lee CH, Gopalakrishnan M, Malysz J. Alpha3* and alpha 7 nAChR-mediated Ca2+ transient generation in IMR-32 neuroblastoma cells. Neurochem Int. 2010 Oct;57(3):269-77. doi: 10.1016/j.neuint.2010.06.005. Epub 2010 Jun 15. PubMed PMID: 20558224. 2: Briggs CA, Grønlien JH, Curzon P, Timmermann DB, Ween H, Thorin-Hagene K, Kerr P, Anderson DJ, Malysz J, Dyhring T, Olsen GM, Peters D, Bunnelle WH, Gopalakrishnan M. Role of channel activation in cognitive enhancement mediated by alpha7 nicotinic acetylcholine receptors. Br J Pharmacol. 2009 Nov;158(6):1486-94. doi: 10.1111/j.1476-5381.2009.00426.x. Epub 2009 Oct 20. PubMed PMID: 19845675; PubMed Central PMCID: PMC2795215. 3: Gopalakrishnan SM, Philip BM, Gronlien JH, Malysz J, Anderson DJ, Gopalakrishnan M, Warrior U, Burns DJ. Functional characterization and high-throughput screening of positive allosteric modulators of α7 nicotinic acetylcholine receptors in IMR-32 neuroblastoma cells. Assay Drug Dev Technol. 2011 Dec;9(6):635-45. doi: 10.1089/adt.2010.0319. Epub 2011 Feb 10. PubMed PMID: 21309712. 4: Grønlien JH, Ween H, Thorin-Hagene K, Cassar S, Li J, Briggs CA, Gopalakrishnan M, Malysz J. Importance of M2-M3 loop in governing properties of genistein at the α7 nicotinic acetylcholine receptor inferred from α7/5-HT3A chimera. Eur J Pharmacol. 2010 Nov 25;647(1-3):37-47. doi: 10.1016/j.ejphar.2010.08.027. Epub 2010 Sep 9. PubMed PMID: 20816816.