MedKoo Cat#: 530937 | Name: TA-02
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.

Chemical Structure

TA-02
TA-02
CAS#1784751-19-4

Theoretical Analysis

MedKoo Cat#: 530937

Name: TA-02

CAS#: 1784751-19-4

Chemical Formula: C20H13F2N3

Exact Mass: 333.1078

Molecular Weight: 333.34

Elemental Analysis: C, 72.06; H, 3.93; F, 11.40; N, 12.61

Price and Availability

Size Price Availability Quantity
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
TA-02, TA 02, TA02
IUPAC/Chemical Name
4-(2-(2-fluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridine
InChi Key
QIFJOFNVIVQRNJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H13F2N3/c21-15-7-5-13(6-8-15)18-19(14-9-11-23-12-10-14)25-20(24-18)16-3-1-2-4-17(16)22/h1-12H,(H,24,25)
SMILES Code
FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=CC=C4F)=N2)C=C1
Appearance
White to off-white solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 333.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wen Q, Tang S, Mo J, Zhang M, Long M, Lu Y, Gan Z. Different activation of STAT1 and STAT2 phosphorylation by IFNc, IFNd, and IFNh in tilapia. Fish Shellfish Immunol. 2024 Sep;152:109776. doi: 10.1016/j.fsi.2024.109776. Epub 2024 Jul 16. PMID: 39019128. 2: Lim H, Madhavan S. Non-paretic leg movements can facilitate cortical drive to the paretic leg in individuals post stroke with severe motor impairment: Implications for motor priming. Eur J Neurosci. 2023 Aug;58(3):2853-2867. doi: 10.1111/ejn.16069. Epub 2023 Jun 24. PMID: 37354080; PMCID: PMC10530620. 3: Li Y, Huang Y, Cai J, Jiang D, Jian JC, Lu YS, Wang B. Establishment of an astrocyte-like cell line from the brain of tilapia (Oreochromis niloticus) for virus pathogenesis and a vitro model of the blood-brain barrier. J Fish Dis. 2022 Oct;45(10):1451-1462. doi: 10.1111/jfd.13674. Epub 2022 Jun 27. PMID: 35758189. 4: Abbas A, Fu Y, Qu Z, Zhao H, Sun Y, Lin Y, Xie J, Cheng J, Jiang D. Isolation and evaluation of the biocontrol potential of Talaromyces spp. against rice sheath blight guided by soil microbiome. Environ Microbiol. 2021 Oct;23(10):5946-5961. doi: 10.1111/1462-2920.15596. Epub 2021 Jun 14. PMID: 33989446.