Synonym
TA-01, TA 01, TA01
IUPAC/Chemical Name
4-(2-(2,6-difluorophenyl)-4-(2-fluorophenyl)-1H-imidazol-5-yl)pyridine
InChi Key
QUGPSRHANXSBSL-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H12F3N3/c21-14-5-2-1-4-13(14)19-18(12-8-10-24-11-9-12)25-20(26-19)17-15(22)6-3-7-16(17)23/h1-11H,(H,25,26)
SMILES Code
FC1=CC=CC=C1C2=C(C3=CC=NC=C3)NC(C4=C(F)C=CC=C4F)=N2
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
351.33
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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Epub 2018 Jul 31. PMID: 30063296; PMCID: PMC6186272.
2: Silva Sousa GL, Nadur NF, de Almeida Peixoto Ferreira L, da Silva Honório T,
Simon A, Cabral LM, Móra Santos ML, Andrade B, de Lima EV, Clarke JR, Castro RN,
Olímpio de Moura R, Kümmerle AE. Discovery of novel thiosemicarbazone-acridine
targeting butyrylcholinesterase with antioxidant, metal complexing and
neuroprotector abilities as potential treatment of Alzheimer's disease: In
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