MedKoo Cat#: 561468 | Name: Diethyl bipy55'DC
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Diethyl bipy55'DC inhibits CP4H activity in cultured cells. The stability of collagen relies on post-translational modifications, the most prevalent being the hydroxylation of collagen strands by collagen prolyl 4-hydroxylases (CP4Hs).

Chemical Structure

Diethyl bipy55'DC
CAS#1762-46-5

Theoretical Analysis

MedKoo Cat#: 561468

Name: Diethyl bipy55'DC

CAS#: 1762-46-5

Chemical Formula: C16H16N2O4

Exact Mass: 300.1110

Molecular Weight: 300.31

Elemental Analysis: C, 63.99; H, 5.37; N, 9.33; O, 21.31

Price and Availability

Size Price Availability Quantity
1g USD 250.00 2 Weeks
5g USD 550.00 2 Weeks
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Related CAS #
No Data
Synonym
Diethyl bipy55'DC;
IUPAC/Chemical Name
Diethyl 2,2'-Bipyridine-5,5'-dicarboxylate
InChi Key
IUNBUYCOAQHBMC-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H16N2O4/c1-3-21-15(19)11-5-7-13(17-9-11)14-8-6-12(10-18-14)16(20)22-4-2/h5-10H,3-4H2,1-2H3
SMILES Code
O=C(C1=CN=C(C2=NC=C(C(OCC)=O)C=C2)C=C1)OCC
Appearance
Solid powder
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 300.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Vasta JD, Andersen KA, Deck KM, Nizzi CP, Eisenstein RS, Raines RT. Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells. ACS chemical biology. 2016;11(1):193-199. doi:10.1021/acschembio.5b00749.