Diethyl pyimDC | CAS#1821370-64-2 | CP4H1 inhibitor

MedKoo Cat#: 561467 | Name: Diethyl pyimDC

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Diethyl pyimDC is an inhibitor of human CP4H1. The stability of collagen relies on post-translational modifications, the most prevalent being the hydroxylation of collagen strands by collagen prolyl 4-hydroxylases (CP4Hs).

Chemical Structure

Diethyl pyimDC

CAS#1821370-64-2

Theoretical Analysis

MedKoo Cat#: 561467

Name: Diethyl pyimDC

CAS#: 1821370-64-2

Chemical Formula: C14H15N3O4

Exact Mass: 289.1063

Molecular Weight: 289.29

Elemental Analysis: C, 58.13; H, 5.23; N, 14.53; O, 22.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Diethyl pyimDC;

IUPAC/Chemical Name

Ethyl 2-(5-Ethoxycarbonyl-1H-imidazol-2-yl)pyridine-5-carboxylate

InChi Key

ZFLMXWJZGZWFQY-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H15N3O4/c1-3-20-13(18)9-5-6-10(15-7-9)12-16-8-11(17-12)14(19)21-4-2/h5-8H,3-4H2,1-2H3,(H,16,17)

SMILES Code

O=C(C1=CN=C(C2=NC=C(C(OCC)=O)N2)C=C1)OCC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 289.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Vasta JD, Andersen KA, Deck KM, Nizzi CP, Eisenstein RS, Raines RT. Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells. ACS chemical biology. 2016;11(1):193-199. doi:10.1021/acschembio.5b00749.