GNE-049 is a potent and selective inhibitor of CBP/p300 bromodomain. GNE-049 blocks prostate cancer growth in vitro and in vivo. Therapeutic targeting of the CBP/p300 bromodomain blocks the growth of castration-resistant prostate cancer.
MedKoo Cat#: 407815
Name: GNE-049
CAS#: 1936421-41-8
Chemical Formula: C26H30F2N6O2
Exact Mass: 496.2398
Molecular Weight: 496.56
Elemental Analysis: C, 62.89; H, 6.09; F, 7.65; N, 16.92; O, 6.44
The following data is based on the product molecular weight 496.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
