MedKoo Cat#: 561458 | Name: STK16-IN-1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

STK16-IN-1 is a highly selective ATP competitive inhibitor of STK16. STK16 has been implicated to function in a variety of cellular processes such as VEGF and cargo secretion.

Chemical Structure

STK16-IN-1
STK16-IN-1
CAS#1223001-53-3

Theoretical Analysis

MedKoo Cat#: 561458

Name: STK16-IN-1

CAS#: 1223001-53-3

Chemical Formula: C17H12FN3O

Exact Mass: 293.0964

Molecular Weight: 293.30

Elemental Analysis: C, 69.62; H, 4.12; F, 6.48; N, 14.33; O, 5.45

Price and Availability

Size Price Availability Quantity
5mg USD 285.00 2 Weeks
10mg USD 500.00 2 Weeks
25mg USD 1,050.00 2 Weeks
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Related CAS #
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Synonym
STK16-IN-1; STK16 IN 1; STK16IN1; JWC-029; JWC 029; JWC029;
IUPAC/Chemical Name
1-(4-Fluoro-3-methylphenyl)-1,7-dihydro-2H-pyrrolo[2,3-h][1,6]naphthyridin-2-one
InChi Key
WQNRDXHKVSKUPI-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H12FN3O/c1-10-8-12(3-4-14(10)18)21-15(22)5-2-11-9-20-17-13(16(11)21)6-7-19-17/h2-9H,1H3,(H,19,20)
SMILES Code
O=C1N(C2=CC=C(F)C(C)=C2)C3=C4C(NC=C4)=NC=C3C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 293.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Liu F, Wang J, Yang X, Li B, Wu H, Qi S, Chen C, Liu X, Yu K, Wang W, Zhao Z, Wang A, Chen Y, Wang L, Gray NS, Liu J, Zhang X, Liu Q. Discovery of a Highly Selective STK16 Kinase Inhibitor. ACS Chem Biol. 2016 Jun 17;11(6):1537-43. doi: 10.1021/acschembio.6b00250. Epub 2016 Apr 22. PubMed PMID: 27082499.