S6K1-IN-DG2 | CAS#871340-88-4 | S6K1 inhibitor

MedKoo Cat#: 561433 | Name: S6K1-IN-DG2

Description:

WARNING: This product is for research use only, not for human or veterinary use.

S6K1-IN-DG2 is a potent and selective inhibitor of p70 ribosomal S6 kinase 1 (S6K1). S6K1-IN-DG2 is also ATP-competitive and cell-permeable.

Chemical Structure

S6K1-IN-DG2

CAS#871340-88-4

Theoretical Analysis

MedKoo Cat#: 561433

Name: S6K1-IN-DG2

CAS#: 871340-88-4

Chemical Formula: C16H17BrN6O

Exact Mass: 388.0647

Molecular Weight: 389.26

Elemental Analysis: C, 49.37; H, 4.40; Br, 20.53; N, 21.59; O, 4.11

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

S6K1 Inhibitor DG2; S6K1-Inhibitor-DG2; S6K1InhibitorDG2; S6K1-IN-DG2; S6K1 IN DG2; S6K1INDG2;

IUPAC/Chemical Name

3-Bromo-4-[4-(2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine

InChi Key

CQXAPCMYRSTDGK-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H17BrN6O/c1-24-12-5-3-2-4-11(12)22-6-8-23(9-7-22)16-13-14(17)20-21-15(13)18-10-19-16/h2-5,10H,6-9H2,1H3,(H,18,19,20,21)

SMILES Code

COC1=CC=CC=C1N2CCN(C3=C4C(NN=C4Br)=NC=N3)CC2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 389.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Okuzumi T, Fiedler D, Zhang C, Gray DC, Aizenstein B, Hoffman R, Shokat KM. Inhibitor hijacking of Akt activation. Nat Chem Biol. 2009 Jul;5(7):484-93. doi: 10.1038/nchembio.183. Epub 2009 May 24. PubMed PMID: 19465931; PubMed Central PMCID: PMC2783590.